This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TOPORS Monoclonal Antibody (4G4)
catalog :
MA5-20967
quantity :
100 ug
price :
US 474.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4G4
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
product information
Product Type :
Antibody
Product Name :
TOPORS Monoclonal Antibody (4G4)
Catalog # :
MA5-20967
Quantity :
100 ug
Price :
US 474.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
ELISA: Assay-Dependent, Immunocytochemistry: 10 ug/mL, Western Blot: 1-5 ug/mL
Species :
Human
Clone :
4G4
Isotype :
IgG2a, kappa
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage-induced cell death through IKBKE sumoylation.
Immunogen :
TOPORS (NP_005793, 98 a.a. ~ 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-Dependent, Immunocytochemistry: 10 ug/mL, Western Blot: 1-5 ug/mL
Aliases :
AW105885; E3 ubiquitin-protein ligase Topors; LUN; p53-binding protein 3; P53BP3; p53BP3/LUN; RING-type E3 ubiquitin transferase Topors; RP31; SUMO1-protein E3 ligase Topors; TOP1 binding arginine/serine rich protein; topoisomerase 1-binding RING finger; topoisomerase I binding, arginine/serine-rich; topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase; topoisomerase I-binding arginine/serine-rich protein; Topoisomerase I-binding RING finger protein; Topors; TP53BPL; tumor suppressor p53-binding protein 3
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA