MEL18 Monoclonal Antibody (3E4) | Invitrogen MA5-20275 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MEL18 Monoclonal Antibody (3E4)

catalog :

MA5-20275

quantity :

100 ug

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3.00E+04

reactivity :

human

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

MEL18 Monoclonal Antibody (3E4)

Catalog # :

MA5-20275

Quantity :

100 ug

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Western Blot: 1-5 ug/mL

Species :

Human

Clone :

3.00E+04

Isotype :

IgG2a, kappa

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.

Immunogen :

PCGF2 (AAH04858.1, 236 a.a. ~ 294 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Western Blot: 1-5 ug/mL

Aliases :

DNA-binding protein Mel-18; Mel18; Mel-18; Melanoma nuclear protein 18; MGC10545; Pcgf2; polycomb group ring finger 2; polycomb group RING finger protein 2; RING finger protein 110; RNF110; Zfp144; Zfp-144; Zinc finger protein 144; zinc finger protein 144 (Mel-18) (human homolog); ZNF144