PLSCR1 Monoclonal Antibody (3B4) | Invitrogen MA5-19636 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PLSCR1 Monoclonal Antibody (3B4)

catalog :

MA5-19636

quantity :

100 µg

price :

US 446

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3B4

reactivity :

human

application :

immunoprecipitation

product information

Product Type :

Antibody

Product Name :

PLSCR1 Monoclonal Antibody (3B4)

Catalog # :

MA5-19636

Quantity :

100 µg

Price :

US 446

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Species :

Human

Clone :

3B4

Isotype :

IgG2a, kappa

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

The calcium-dependent plasma membrane protein phospholipid scramblase 1 (PLSCR1) contributes to the transbilayer movement of phosphatidylserine and other membrane phospholipids upon influx of calcium into the cytosol. This movement results in plasma membrane phospholipid remodelling and surface exposure of phosphatidylserine in injured or apoptotic cells, which leads to cell death. Interferons and other cytokines induce expression of PLSCR1, implying that PLSCR1 also functions in cytokine signaling pathways. EGF stilmulation results in tyrosine phosphorylation of PLSCR1 on tyrosines 69 and 74, which allows it to interact with Shc, and thereby connecting Src kinase activation to stimulation of the EGF receptor.

Immunogen :

PLSCR1 (AAH32718, 1 a.a. ~ 318 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Immunoprecipitation: Assay-Dependent

Aliases :

Ca(2+)-dependent phospholipid scramblase 1; erythrocyte phospholipid scramblase; MmTRA1a; MmTRA1b; NOR1; Phospholipid scramblase 1; phospholipid scramblase 2; PL scramblase 1; PLSCR1; Tra1; Tra1a; Tra1b; Transplantability-associated protein 1; Tras1; Tras2