LIN7A Monoclonal Antibody (P377) | Invitrogen MA5-18298 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LIN7A Monoclonal Antibody (P377)

catalog :

MA5-18298

quantity :

100 uL

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

P377

reactivity :

human

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

LIN7A Monoclonal Antibody (P377)

Catalog # :

MA5-18298

Quantity :

100 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:500-1:3,000

Species :

Human

Clone :

P377

Isotype :

IgG2b

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 12 and 227 of LIN7A

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:500-1:3,000

Aliases :

AI848705; hLin-7; lin 7 homolog a; LIN7; lin-7 homolog A (C. elegans); lin-7 homolog A, crumbs cell polarity complex component; Lin7a; lin-7A; lin-7-Ba; Mals1; MALS-1; mammalian LIN-7 1; mammalian lin-seven protein 1; mLin-7; protein lin-7 homolog A; Tax interaction protein 33; TIP-33; Veli; Veli1; veli-1; veli-1 protein; vertebrate homolog of C. elegans Lin-7 type 1; vertebrate LIN7 homolog 1; vertebrate lin-7 homolog 1