Transferrin Receptor Monoclonal Antibody (MEM-75), Alexa Fluor 647

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Transferrin Receptor Monoclonal Antibody (MEM-75), Alexa Fluor 647

catalog :

MA5-18151

quantity :

100 Tests

price :

US 435.00

clonality :

monoclonal

host :

mouse

conjugate :

AF647

clone name :

MEM-75

The same clone is also sold as:

Abcam: ab187777, ab28116, ab9179, ab18242, ab239251
Exbio: A7-235-T025, A7-235-T100, 1F-235-T100, 1B-235-C025, A6-235-T025, T4-235-T100, 1A-235-T025, 11-235-C025, 1P-235-T100, 1A-235-T100, T4-235-T025, 11-235-C100, 1P-235-T025, 1B-235-C100, A6-235-T100, T9-235-T100, PB-235-T025, PB-235-T100, 1F-235-T025
OriGene: SM3104F, SM3104APC, SM3104P, SM3104R, SM3104B

reactivity :

human

application :

immunocytochemistry, flow cytometry

citations: 1

Reference
Geles K, Gao Y, Giannakou A, Sridharan L, Yamin T, Zhang J, et al. NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells. Cell Rep Med. 2021;2:100279 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Transferrin Receptor Monoclonal Antibody (MEM-75), Alexa Fluor 647

Catalog # :

MA5-18151

Quantity :

100 Tests

Price :

US 435.00

Clonality :

Monoclonal

Purity :

Size-exclusion chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 4 uLx100 uL whole blood or 10^6 cells, Immunocytochemistry: Assay-dependent

Species :

Human

Clone :

MEM-75

Isotype :

IgG1

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

Immunogen :

NALM-6 human pre-B cell line

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 4 uLx100 uL whole blood or 10^6 cells, Immunocytochemistry: Assay-dependent

Aliases :

2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr