Nesprin 2 Monoclonal Antibody (K20-478-5) | Invitrogen MA5-18075 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Nesprin 2 Monoclonal Antibody (K20-478-5)

catalog :

MA5-18075

quantity :

100 µL

price :

US 582

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

K20-478-5

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:100; loading ...; fig s2e	Yokoi A, Villar Prados A, Oliphint P, Zhang J, Song X, De Hoff P, et al. Mechanisms of nuclear content loading to exosomes. Sci Adv. 2019;5:eaax8849 pubmed publisher
immunocytochemistry; human; 1:1000; loading ...; fig s9a	Takaki T, Montagner M, Serres M, Le Berre M, Russell M, Collinson L, et al. Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability. Nat Commun. 2017;8:16013 pubmed publisher
	Spriggs C, Cha G, Li J, Tsai B. Components of the LINC and NPC complexes coordinately target and translocate a virus into the nucleus to promote infection. PLoS Pathog. 2022;18:e1010824 pubmed publisher
	Kidiyoor G, Li Q, Bastianello G, Bruhn C, Giovannetti I, Mohamood A, et al. ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration. Nat Commun. 2020;11:4828 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Nesprin 2 Monoclonal Antibody (K20-478-5)

Catalog # :

MA5-18075

Quantity :

100 µL

Price :

US 582

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 1:500, Immunomicroscopy: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:2,500

Species :

Human

Clone :

K20-478-5

Isotype :

IgG2b, kappa

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Residues 1-459 of human Nesprin-2

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:500, Immunomicroscopy: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:2,500

Aliases :

6820443O06Rik; AW546258; D12Ertd777e; EDMD5; KASH domain-containing protein 2; KASH2; KIAA1011; MGC96690; mKIAA1011; Nesp2; Nesp2g; nesprin 2; nesprin-2; NUA; NUANCE; nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; polytrophin; Protein NUANCE; spectrin repeat containing nuclear envelope protein 2; spectrin repeat containing, nuclear envelope 2; synaptic nuclear envelope 2; synaptic nuclear envelope protein 2; synaptic nuclei expressed gene 2; SYNE2; Syne-2; TROPH

more info or order :

Invitrogen product webpage