Progerin Monoclonal Antibody (13A4D4) | Invitrogen MA5-18073 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Progerin Monoclonal Antibody (13A4D4)

catalog :

MA5-18073

quantity :

100 uL

price :

US 582.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13A4D4

The same clone is also sold as:

Santa Cruz Biotechnology: sc-81611 HRP, sc-81611, sc-81611 AC

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

Progerin Monoclonal Antibody (13A4D4)

Catalog # :

MA5-18073

Quantity :

100 uL

Price :

US 582.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:200- 1:500

Species :

Human

Clone :

13A4D4

Isotype :

IgG1, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Progerin is a 614 amino acid protein involved in Hutchinson-Gilford progeria syndrome. Progerin is most often generated by a point mutation (C1824T) in the LMNA gene that codes for lamin-A/C. This mutation activates a cryptic splice site and gives rise to a form of lamin A with a 50-amino acid internal deletion within the C-terminal domain of the protein. Approximately 80% of Hutchinson-Gilford progeria syndrome cases carry a single copy of the most common mutation, a silent point mutation, G608G (GGC > GGT), within exon 11 of the LMNA gene.

Immunogen :

Synthetic peptide conjugated to KLH derived from within residues 604-611 (GAQSPQNC) at the C terminus of Human Progerin

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:200- 1:500

Aliases :

70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A/C; lamin A/C-like 1; Lamin AC; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; Mutant lamin A/C; Prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32