This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PP2A B-alpha Monoclonal Antibody (2G9)
catalog :
MA5-18064
quantity :
100 uL
price :
US 592.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2G9

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 1
Reference
Williams B, Filter J, Blake Hodek K, Wadzinski B, Fuda N, Shalloway D, et al. Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers. elife. 2014;3:e01695 pubmed publisher
product information
Product Type :
Antibody
Product Name :
PP2A B-alpha Monoclonal Antibody (2G9)
Catalog # :
MA5-18064
Quantity :
100 uL
Price :
US 592.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
Species :
Human, Mouse, Rat
Clone :
2G9
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
PPP2R2A (Protein Phosphatase 2 Regulatory Subunit Balpha) is a Protein Coding gene. Diseases associated with PPP2R2A include Lung Cancer and Hepatocellular Carcinoma. Among its related pathways are 'Cell Cycle, Mitotic' and p70S6K Signaling. Gene Ontology (GO) annotations related to this gene include protein serine/threonine phosphatase activity and protein phosphatase regulator activity. An important paralog of this gene is PPP2R2D. The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Essential for serine/threonine-protein phosphatase 2A-mediated dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint. The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described.
Immunogen :
Peptide from rat PP2A isoform alpha (Immunogen sequence: 398-CASGKRKKDEISVD-411)
Format :
Liquid
Applications w/Dilutions :
Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA