CD105 Monoclonal Antibody (MJ7/18) | Invitrogen MA5-17943 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD105 Monoclonal Antibody (MJ7/18)

catalog :

MA5-17943

quantity :

250 ug

price :

US 414.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

MJ7/18

reactivity :

mouse

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:100; loading ...; fig 9a	V gtle T, Sharma S, Mori J, Nagy Z, Semeniak D, Scandola C, et al. Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B. elife. 2019;8: pubmed publisher
flow cytometry; mouse; fig s2	Cañete A, Carmona R, Ariza L, Sanchez M, Rojas A, Muñoz Chápuli R. A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice. Haematologica. 2017;102:647-655 pubmed publisher
flow cytometry; mouse; loading ...; fig ex5f	Hoppe P, Schwarzfischer M, Loeffler D, Kokkaliaris K, Hilsenbeck O, Moritz N, et al. Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios. Nature. 2016;535:299-302 pubmed publisher
flow cytometry; mouse; fig 1e	Yu Q, Song W, Wang D, Zeng Y. Identification of blood vascular endothelial stem cells by the expression of protein C receptor. Cell Res. 2016;26:1079-1098 pubmed publisher
flow cytometry; mouse; loading ...; fig s2b	Abramowski P, Krasemann S, Ernst T, Lange C, Ittrich H, Schweizer M, et al. Mesenchymal Stromal/Stem Cells Do Not Ameliorate Experimental Autoimmune Encephalomyelitis and Are Not Detectable in the Central Nervous System of Transplanted Mice. Stem Cells Dev. 2016;25:1134-48 pubmed publisher
flow cytometry; mouse; loading ...; fig 2	Patenaude J, Perreault C. Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile. J Immunol. 2016;196:4760-70 pubmed publisher
flow cytometry; mouse; loading ...; fig 1	Woods S, Waite A, O Dea K, Halford P, Takata M, Wilson M. Kinetic profiling of in vivo lung cellular inflammatory responses to mechanical ventilation. Am J Physiol Lung Cell Mol Physiol. 2015;308:L912-21 pubmed publisher
	Gallardo Vara E, Tual Chalot S, Botella L, Arthur H, Bernabeu C. Soluble endoglin regulates expression of angiogenesis-related proteins and induction of arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia. Dis Model Mech. 2018;11: pubmed publisher
	Durai V, Bagadia P, Briseño C, Theisen D, Iwata A, Davidson J, et al. Altered compensatory cytokine signaling underlies the discrepancy between Flt3-/- and Flt3l-/- mice. J Exp Med. 2018;215:1417-1435 pubmed publisher
	Onodera Y, Teramura T, Takehara T, Obora K, Mori T, Fukuda K. miR-155 induces ROS generation through downregulation of antioxidation-related genes in mesenchymal stem cells. Aging Cell. 2017;16:1369-1380 pubmed publisher
	Uckelmann H, Blaszkiewicz S, Nicolae C, Haas S, Schnell A, Wurzer S, et al. Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4. J Exp Med. 2016;213:1961-71 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD105 Monoclonal Antibody (MJ7/18)

Catalog # :

MA5-17943

Quantity :

250 ug

Price :

US 414.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 ug/1x10^6 cells, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Mouse

Clone :

MJ7/18

Isotype :

IgG2a, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

Immunogen :

Rat monoclonal antibody raised against inflamed mouse skin.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 ug/1x10^6 cells, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein

more info or order :

Invitrogen product webpage