product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD44 Monoclonal Antibody (IM7.8.1), FITC
catalog :
MA5-17878
quantity :
100 ug
price :
US 242.00
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
IM7.8.1
reactivity :
mouse
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 17
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 6
Ding Z, Bergman A, Rutemark C, Ouchida R, Ohno H, Wang J, et al. Complement-activating IgM enhances the humoral but not the T cell immune response in mice. PLoS ONE. 2013;8:e81299 pubmed publisher
  • flow cytometry; mouse
Yassai M, Cooley B, Gorski J. Developmental dynamics of post-selection thymic DN iNKT. PLoS ONE. 2012;7:e43509 pubmed publisher
  • flow cytometry; mouse; fig 2
Shameli A, Clemente Casares X, Wang J, Santamaria P. Development of memory-like autoregulatory CD8+ T cells is CD4+ T cell dependent. J Immunol. 2011;187:2859-66 pubmed publisher
  • flow cytometry; mouse; tbl 1
Echeverry A, Saijo S, Schesser K, Adkins B. Yersinia enterocolitica promotes robust mucosal inflammatory T-cell immunity in murine neonates. Infect Immun. 2010;78:3595-608 pubmed publisher
  • flow cytometry; mouse
Tsumiyama K, Miyazaki Y, Shiozawa S. Self-organized criticality theory of autoimmunity. PLoS ONE. 2009;4:e8382 pubmed publisher
  • flow cytometry; mouse
Getahun A, Heyman B. Studies on the mechanism by which antigen-specific IgG suppresses primary antibody responses: evidence for epitope masking and decreased localization of antigen in the spleen. Scand J Immunol. 2009;70:277-87 pubmed publisher
  • flow cytometry; mouse
Getahun A, Hjelm F, Heyman B. IgE enhances antibody and T cell responses in vivo via CD23+ B cells. J Immunol. 2005;175:1473-82 pubmed
  • flow cytometry; mouse; fig 3
Kelchtermans H, De Klerck B, Mitera T, Van Balen M, Bullens D, Billiau A, et al. Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-gamma. Arthritis Res Ther. 2005;7:R402-15 pubmed
  • flow cytometry; mouse
Hsu S, Wu C, Han J, Lai M. Involvement of p38 mitogen-activated protein kinase in different stages of thymocyte development. Blood. 2003;101:970-6 pubmed
  • flow cytometry; mouse
Yu C, Feng M, Shih H, Lai M. Increased p300 expression inhibits glucocorticoid receptor-T-cell receptor antagonism but does not affect thymocyte positive selection. Mol Cell Biol. 2002;22:4556-66 pubmed
  • flow cytometry; mouse; fig 1
Ohmura K, Kawamoto H, Lu M, Ikawa T, Ozaki S, Nakao K, et al. Immature multipotent hemopoietic progenitors lacking long-term bone marrow-reconstituting activity in the aorta-gonad-mesonephros region of murine day 10 fetuses. J Immunol. 2001;166:3290-6 pubmed
  • flow cytometry; mouse; fig 1
Broeren C, Gray G, Carreno B, June C. Costimulation light: activation of CD4+ T cells with CD80 or CD86 rather than anti-CD28 leads to a Th2 cytokine profile. J Immunol. 2000;165:6908-14 pubmed
  • flow cytometry; mouse
Kang J, Coles M, Raulet D. Defective development of gamma/delta T cells in interleukin 7 receptor-deficient mice is due to impaired expression of T cell receptor gamma genes. J Exp Med. 1999;190:973-82 pubmed
  • flow cytometry; mouse
Zerrahn J, Volkmann A, Coles M, Held W, Lemonnier F, Raulet D. Class I MHC molecules on hematopoietic cells can support intrathymic positive selection of T cell receptor transgenic T cells. Proc Natl Acad Sci U S A. 1999;96:11470-5 pubmed
  • flow cytometry; mouse
Pihlgren M, Arpin C, Walzer T, Tomkowiak M, Thomas A, Marvel J, et al. Memory CD44(int) CD8 T cells show increased proliferative responses and IFN-gamma production following antigenic challenge in vitro. Int Immunol. 1999;11:699-706 pubmed
  • flow cytometry; mouse
Kim C, Pelus L, White J, Broxmeyer H. Differential chemotactic behavior of developing T cells in response to thymic chemokines. Blood. 1998;91:4434-43 pubmed
  • flow cytometry; mouse
Pihlgren M, Dubois P, Tomkowiak M, Sjogren T, Marvel J. Resting memory CD8+ T cells are hyperreactive to antigenic challenge in vitro. J Exp Med. 1996;184:2141-51 pubmed
product information
Product Type :
Antibody
Product Name :
CD44 Monoclonal Antibody (IM7.8.1), FITC
Catalog # :
MA5-17878
Quantity :
100 ug
Price :
US 242.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 ug/1x10^6 cells
Species :
Mouse
Clone :
IM7.8.1
Isotype :
IgG2b
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles. Store in the dark.
Description :
CD44 cell surface antigen is a 100 kDa type 1 transmembrane glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential. CD44 is expressed by hematopoietic, non-hematopoietic cells, epithelial tissues, and to filopodia in cultured keratinocytes. Further, bone marrow myeloid cells and memory T cells express CD44 at high levels, and peripheral B and T cells can upregulate the expression of CD44 in response to certain stimulatory events. Transcripts for the CD44 gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full-length nature of some of these variants have not been determined. Alternative splicing is the basis for the structural and functional diversity of the CD44 protein. Diseases associated with CD44 dysfunction include superficial keratitis and lichen sclerosus. CD44 also may be related to tumor metastasis formation.
Immunogen :
Mouse CD44
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/1x10^6 cells
Aliases :
AU023126; AW121933; AW146109; Bovine CD44; CD44; CD44 antigen; CD44 antigen-like protein; CD44 molecule; CD44 molecule (Indian blood group); CD44 protein; CD44 variant; CD44A; CD44-like protein; CDW44; cell surface glycoprotein CD44; Cell surface glycoprotein CD44 (hyaluronate binding protein); cell-surface glycoprotein; chondroitin sulfate proteoglycan 8; CSPG8; ECMRIII; ECMR-III; Epican; extracellular matrix receptor III; extracellular matrix receptor-III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; HERMES; Hermes antigen; homing function and Indian blood group system; HUTCH-I; hyaluronan receptor; Hyaluronate receptor; IN; LHR; Ly-24; lymphocyte antigen 24; lymphocyte surface antigen precursor CD44; MC56; MDU2; MDU3; METAA; MIC4; PGP I; Pgp1; PGP-1; PGPI; PGP-I; Phagocytic glycoprotein 1; phagocytic glycoprotein I; putative Bos taurus CD44; RHAMM; sCD 44; sCD44; soluble CD 44; soluble CD44
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA