product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD62L Monoclonal Antibody (MEL-14), PE
catalog :
MA5-17802
quantity :
50 ug
price :
US 191.00
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
MEL-14
reactivity :
human, mouse
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 26
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s5c
Svensson M, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody K, et al. Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal. Sci Adv. 2020;6:eaba4353 pubmed publisher
  • flow cytometry; human; 1:100; loading ...; fig 6a
Gao M, Wang T, Ji L, Bai S, Tian L, Song H. Therapy With Carboplatin and Anti-PD-1 Antibodies Before Surgery Demonstrates Sustainable Anti-Tumor Effects for Secondary Cancers in Mice With Triple-Negative Breast Cancer. Front Immunol. 2020;11:366 pubmed publisher
  • flow cytometry; mouse; loading ...; fig e10
Majer O, Liu B, Kreuk L, Krogan N, Barton G. UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity. Nature. 2019;575:366-370 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3c
Cordova Z, Grönholm A, Kytölä V, Taverniti V, Hämäläinen S, Aittomäki S, et al. Myeloid cell expressed proprotein convertase FURIN attenuates inflammation. Oncotarget. 2016;7:54392-54404 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2e
Lowe K, Navarro Núñez L, Bénézech C, Nayar S, Kingston B, Nieswandt B, et al. The expression of mouse CLEC-2 on leucocyte subsets varies according to their anatomical location and inflammatory state. Eur J Immunol. 2015;45:2484-93 pubmed publisher
  • flow cytometry; mouse; fig 1
Sadri N, Lu J, Badura M, Schneider R. AUF1 is involved in splenic follicular B cell maintenance. BMC Immunol. 2010;11:1 pubmed publisher
  • flow cytometry; mouse; fig 2
Merck E, Voyle R, MacDonald H. Ly49D engagement on T lymphocytes induces TCR-independent activation and CD8 effector functions that control tumor growth. J Immunol. 2009;182:183-92 pubmed
  • flow cytometry; mouse; fig 2D
Stephens G, Andersson J, Shevach E. Distinct subsets of FoxP3+ regulatory T cells participate in the control of immune responses. J Immunol. 2007;178:6901-11 pubmed
  • flow cytometry; mouse; fig 3
Hofmann M, Brinkmann V, Zerwes H. FTY720 preferentially depletes naive T cells from peripheral and lymphoid organs. Int Immunopharmacol. 2006;6:1902-10 pubmed
  • flow cytometry; mouse
Hofmann M, Zerwes H. Identification of organ-specific T cell populations by analysis of multiparameter flow cytometry data using DNA-chip analysis software. Cytometry A. 2006;69:533-40 pubmed
  • flow cytometry; mouse
Mischenko V, Kapina M, Eruslanov E, Kondratieva E, Lyadova I, Young D, et al. Mycobacterial dissemination and cellular responses after 1-lobe restricted tuberculosis infection of genetically susceptible and resistant mice. J Infect Dis. 2004;190:2137-45 pubmed
  • flow cytometry; mouse
Tchilian E, Dawes R, Hyland L, Montoya M, Le Bon A, Borrow P, et al. Altered CD45 isoform expression affects lymphocyte function in CD45 Tg mice. Int Immunol. 2004;16:1323-32 pubmed
  • flow cytometry; mouse; fig 6
Ishihara K, Sawa S, Ikushima H, Hirota S, Atsumi T, Kamimura D, et al. The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis. Int Immunol. 2004;16:455-65 pubmed
  • flow cytometry; mouse; fig 5
Tardivel A, Tinel A, Lens S, Steiner Q, Sauberli E, Wilson A, et al. The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF. Eur J Immunol. 2004;34:509-18 pubmed
  • flow cytometry; mouse
Eruslanov E, Majorov K, Orlova M, Mischenko V, Kondratieva T, Apt A, et al. Lung cell responses to M. tuberculosis in genetically susceptible and resistant mice following intratracheal challenge. Clin Exp Immunol. 2004;135:19-28 pubmed
  • flow cytometry; mouse
Noble A, Leggat J, Inderberg E. CD8+ immunoregulatory cells in the graft-versus-host reaction: CD8 T cells activate dendritic cells to secrete interleukin-12/interleukin-18 and induce T helper 1 autoantibody. Immunology. 2003;109:476-86 pubmed
  • flow cytometry; mouse; fig 4, 5
Wu T, Lee J, Lai Y, Hsu J, Tsai C, Lee Y, et al. Reduced expression of Bcl-2 in CD8+ T cells deficient in the IL-15 receptor alpha-chain. J Immunol. 2002;168:705-12 pubmed
  • flow cytometry; mouse
Schneider P, Takatsuka H, Wilson A, Mackay F, Tardivel A, Lens S, et al. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J Exp Med. 2001;194:1691-7 pubmed
  • flow cytometry; mouse; fig 4
Campbell D, Kim C, Butcher E. Separable effector T cell populations specialized for B cell help or tissue inflammation. Nat Immunol. 2001;2:876-81 pubmed
  • flow cytometry; mouse; fig 2
Attinger A, MacDonald H, Acha Orbea H. Lymphoid environment limits superantigen and antigen-induced T cell proliferation at high precursor frequency. Eur J Immunol. 2001;31:884-93 pubmed
  • flow cytometry; mouse; fig 1
Jelley Gibbs D, Lepak N, Yen M, Swain S. Two distinct stages in the transition from naive CD4 T cells to effectors, early antigen-dependent and late cytokine-driven expansion and differentiation. J Immunol. 2000;165:5017-26 pubmed
  • flow cytometry; mouse; fig 1
Eberl G, Lees R, Smiley S, Taniguchi M, Grusby M, MacDonald H. Tissue-specific segregation of CD1d-dependent and CD1d-independent NK T cells. J Immunol. 1999;162:6410-9 pubmed
  • flow cytometry; mouse
Katakai T, Mori K, Masuda T, Shimizu A. Differential localization of Th1 and Th2 cells in autoimmune gastritis. Int Immunol. 1998;10:1325-34 pubmed
  • flow cytometry; mouse
Liu L, Rich B, Inobe J, Chen W, Weiner H. Induction of Th2 cell differentiation in the primary immune response: dendritic cells isolated from adherent cell culture treated with IL-10 prime naive CD4+ T cells to secrete IL-4. Int Immunol. 1998;10:1017-26 pubmed
Goldberg G, Cornish A, Murphy J, Pang E, Lim L, Campbell I, et al. G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis. Am J Pathol. 2016;186:172-84 pubmed publisher
Newrzela S, Cornils K, Heinrich T, Schläger J, Yi J, Lysenko O, et al. Retroviral insertional mutagenesis can contribute to immortalization of mature T lymphocytes. Mol Med. 2011;17:1223-32 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD62L Monoclonal Antibody (MEL-14), PE
Catalog # :
MA5-17802
Quantity :
50 ug
Price :
US 191.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: Assay-dependent
Species :
Mouse
Clone :
MEL-14
Isotype :
IgG2a
Storage :
4 C, do not freeze
Description :
The human CD62L is a 74-95 kDa glycoprotein member of the selectin family of adhesion receptors. L-Selectin is comprised of an aminoterminal C-type lectin binding domain, an epidermal growth factor-like domain, two short consensus repeat (SCR) sequences homologous to those found in complement binding proteins, a short spacer region, a transmembrane region and a short cytoplasmic region. Human CD62L (L-Selectin) is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes and polymorphonuclear cells.
Immunogen :
Mouse B cell Lymphoma, 38C-14. Donor: Fischer Rat Spleen
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-dependent
Aliases :
A.11; AI528707; CD62 antigen-like family member L; CD62L; gp90-MEL; hLHRc; LAM1; LAM-1; LECAM1; LECAM-1; LEU8; Leu-8; Leukocyte adhesion molecule 1; leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LNHR; LSEL; L-selectin; Ly22; Ly-22; LYAM1; Lyam-1; Ly-m22; Lymph node homing receptor; lymphocyte adhesion molecule 1; lymphocyte antigen 22; Lymphocyte surface MEL-14 antigen; pln homing receptor; PLNHR; SELE; selectin E (endothelial adhesion molecule 1); selectin L; selectin L (lymphocyte adhesion molecule 1); selectin, lymphocyte; Sell; TQ1
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA