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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD90 Monoclonal Antibody (5a-8), Biotin
catalog :
MA5-17745
quantity :
100 ug
price :
US 252.00
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
5a-8
reactivity :
mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section, other
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • other; mouse
Garcia Ojeda M, Dejbakhsh Jones S, Chatterjea Matthes D, Mukhopadhyay A, BitMansour A, Weissman I, et al. Stepwise development of committed progenitors in the bone marrow that generate functional T cells in the absence of the thymus. J Immunol. 2005;175:4363-73 pubmed
  • flow cytometry; mouse; fig 1
Chatterjea Matthes D, Garcia Ojeda M, Dejbakhsh Jones S, Jerabek L, Manz M, Weissman I, et al. Early defect prethymic in bone marrow T cell progenitors in athymic nu/nu mice. J Immunol. 2003;171:1207-15 pubmed
  • flow cytometry; mouse
Hoffmann P, Ermann J, Edinger M, Fathman C, Strober S. Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J Exp Med. 2002;196:389-99 pubmed
  • flow cytometry; mouse; fig 1, 2
Lan F, Zeng D, Higuchi M, Huie P, Higgins J, Strober S. Predominance of NK1.1+TCR alpha beta+ or DX5+TCR alpha beta+ T cells in mice conditioned with fractionated lymphoid irradiation protects against graft-versus-host disease: "natural suppressor" cells. J Immunol. 2001;167:2087-96 pubmed
  • flow cytometry; mouse
Dejbakhsh Jones S, Garcia Ojeda M, Chatterjea Matthes D, Zeng D, Strober S. Clonable progenitors committed to the T lymphocyte lineage in the mouse bone marrow; use of an extrathymic pathway. Proc Natl Acad Sci U S A. 2001;98:7455-60 pubmed
  • flow cytometry; mouse
Lan F, Zeng D, Huie P, Higgins J, Strober S. Allogeneic bone marrow cells that facilitate complete chimerism and eliminate tumor cells express both CD8 and T-cell antigen receptor-alphabeta. Blood. 2001;97:3458-65 pubmed
  • flow cytometry; mouse
Dejbakhsh Jones S, Strober S. Identification of an early T cell progenitor for a pathway of T cell maturation in the bone marrow. Proc Natl Acad Sci U S A. 1999;96:14493-8 pubmed
  • flow cytometry; mouse; fig 4
Rathmell J, Goodnow C. Effects of the lpr mutation on elimination and inactivation of self-reactive B cells. J Immunol. 1994;153:2831-42 pubmed
product information
Product Type :
Antibody
Product Name :
CD90 Monoclonal Antibody (5a-8), Biotin
Catalog # :
MA5-17745
Quantity :
100 ug
Price :
US 252.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Mouse
Applications :
Flow Cytometry: 1.0 ug/1x10^6 cells, Immunohistochemistry (Frozen): Assay-dependent
Species :
Mouse
Clone :
5a-8
Isotype :
IgG2b, kappa
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. CD90 is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. CD90 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. CD90 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of CD90 led to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor. Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.
Immunogen :
CBA/J
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1.0 ug/1x10^6 cells, Immunohistochemistry (Frozen): Assay-dependent
Aliases :
CD7; CD90; CDw90; FLJ33325; membrane glycoprotein; T25; Thy 1.2; THY1; Thy-1; Thy-1 antigen; Thy-1 cell surface antigen; thy-1 glycoprotein; thy-1 membrane glycoprotein; Thy-1 protein; Thy-1 T-cell antigen; Thy1.1; Thy1.2; Thy-1.2; thymus cell antigen 1, theta; Thymus cell surface antigen
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA