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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TCR DO11.10 Monoclonal Antibody (KJ1-26), PE
catalog :
MA5-17663
quantity :
50 ug
price :
US 371.00
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
KJ1-26
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 26
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 1
Jaffar Z, Ferrini M, Herritt L, Roberts K. Cutting edge: lung mucosal Th17-mediated responses induce polymeric Ig receptor expression by the airway epithelium and elevate secretory IgA levels. J Immunol. 2009;182:4507-11 pubmed publisher
  • flow cytometry; mouse
Hibi M, Hachimura S, Somaya T, Toda E, Hashiguchi M, Takayama T, et al. Splenic Dendritic Cells from Antigen-Fed Mice Induced Antigen-Specific T Cell Unresponsiveness in vivo. Cytotechnology. 2003;43:41-8 pubmed
  • flow cytometry; mouse; fig 1
Adeeku E, Gudapati P, Mendez Fernandez Y, Van Kaer L, Boothby M. Flexibility accompanies commitment of memory CD4 lymphocytes derived from IL-4 locus-activated precursors. Proc Natl Acad Sci U S A. 2008;105:9307-12 pubmed publisher
  • flow cytometry; mouse; fig 2d
Kanzato H, Fujiwara S, Ise W, Kaminogawa S, Sato R, Hachimura S. Lactobacillus acidophilus strain L-92 induces apoptosis of antigen-stimulated T cells by modulating dendritic cell function. Immunobiology. 2008;213:399-408 pubmed publisher
  • flow cytometry; mouse; fig 3
Manni M, Maestroni G. Sympathetic nervous modulation of the skin innate and adaptive immune response to peptidoglycan but not lipopolysaccharide: involvement of beta-adrenoceptors and relevance in inflammatory diseases. Brain Behav Immun. 2008;22:80-8 pubmed
  • flow cytometry; mouse
Arredouani M, Franco F, Imrich A, Fedulov A, Lu X, Perkins D, et al. Scavenger Receptors SR-AI/II and MARCO limit pulmonary dendritic cell migration and allergic airway inflammation. J Immunol. 2007;178:5912-20 pubmed
  • flow cytometry; mouse
Marski M, Ye A, Abraham C. CD18 is required for intestinal T cell responses at multiple immune checkpoints. J Immunol. 2007;178:2104-12 pubmed
  • flow cytometry; mouse; fig 2A
MacKenzie D, Schartner J, Lin J, Timmel A, Jennens Clough M, Fathman C, et al. GRAIL is up-regulated in CD4+ CD25+ T regulatory cells and is sufficient for conversion of T cells to a regulatory phenotype. J Biol Chem. 2007;282:9696-702 pubmed
  • flow cytometry; mouse; fig 2
Coleman C, Howell K, Hobbs M, Riggs J. Age-dependent loss of naïve T cells in TCR transgenic bone marrow chimeras. Immunobiology. 2006;211:701-9 pubmed
  • flow cytometry; mouse
Berenson L, Yang J, Sleckman B, Murphy T, Murphy K. Selective requirement of p38alpha MAPK in cytokine-dependent, but not antigen receptor-dependent, Th1 responses. J Immunol. 2006;176:4616-21 pubmed
  • flow cytometry; mouse
Marski M, Kandula S, Turner J, Abraham C. CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells. J Immunol. 2005;175:7889-97 pubmed
  • flow cytometry; mouse
Sangaletti S, Gioiosa L, Guiducci C, Rotta G, Rescigno M, Stoppacciaro A, et al. Accelerated dendritic-cell migration and T-cell priming in SPARC-deficient mice. J Cell Sci. 2005;118:3685-94 pubmed
  • flow cytometry; mouse
DeRyckere D, DeGregori J. E2F1 and E2F2 are differentially required for homeostasis-driven and antigen-induced T cell proliferation in vivo. J Immunol. 2005;175:647-55 pubmed
  • flow cytometry; mouse
Wille Reece U, Wu C, Flynn B, Kedl R, Seder R. Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses. J Immunol. 2005;174:7676-83 pubmed
  • flow cytometry; mouse; fig 2
Shin T, Yoshimura K, Shin T, Crafton E, Tsuchiya H, Housseau F, et al. In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses. J Exp Med. 2005;201:1531-41 pubmed
  • flow cytometry; mouse; fig 2
Hammad H, de Vries V, Maldonado Lopez R, Moser M, Maliszewski C, Hoogsteden H, et al. Differential capacity of CD8+ alpha or CD8- alpha dendritic cell subsets to prime for eosinophilic airway inflammation in the T-helper type 2-prone milieu of the lung. Clin Exp Allergy. 2004;34:1834-40 pubmed
  • flow cytometry; mouse; fig 1
Kuipers H, Heirman C, Hijdra D, Muskens F, Willart M, Van Meirvenne S, et al. Dendritic cells retrovirally overexpressing IL-12 induce strong Th1 responses to inhaled antigen in the lung but fail to revert established Th2 sensitization. J Leukoc Biol. 2004;76:1028-38 pubmed
  • flow cytometry; mouse; fig 3
Dooms H, Kahn E, Knoechel B, Abbas A. IL-2 induces a competitive survival advantage in T lymphocytes. J Immunol. 2004;172:5973-9 pubmed
  • flow cytometry; mouse; fig 1
Zhou P, Borojevic R, Streutker C, Snider D, Liang H, Croitoru K. Expression of dual TCR on DO11.10 T cells allows for ovalbumin-induced oral tolerance to prevent T cell-mediated colitis directed against unrelated enteric bacterial antigens. J Immunol. 2004;172:1515-23 pubmed
  • flow cytometry; mouse
Hammad H, de Heer H, Soullie T, Angeli V, Trottein F, Hoogsteden H, et al. Activation of peroxisome proliferator-activated receptor-gamma in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma. Am J Pathol. 2004;164:263-71 pubmed
  • flow cytometry; mouse; fig 4
Hammad H, de Heer H, Soullie T, Hoogsteden H, Trottein F, Lambrecht B. Prostaglandin D2 inhibits airway dendritic cell migration and function in steady state conditions by selective activation of the D prostanoid receptor 1. J Immunol. 2003;171:3936-40 pubmed
  • flow cytometry; mouse; fig 4
Kuipers H, Hijdra D, de Vries V, Hammad H, Prins J, Coyle A, et al. Lipopolysaccharide-induced suppression of airway Th2 responses does not require IL-12 production by dendritic cells. J Immunol. 2003;171:3645-54 pubmed
  • flow cytometry; mouse; fig 5
Angeli V, Hammad H, Staels B, Capron M, Lambrecht B, Trottein F. Peroxisome proliferator-activated receptor gamma inhibits the migration of dendritic cells: consequences for the immune response. J Immunol. 2003;170:5295-301 pubmed
  • flow cytometry; mouse
Rigby S, Rouse T, Field E. Total lymphoid irradiation nonmyeloablative preconditioning enriches for IL-4-producing CD4+-TNK cells and skews differentiation of immunocompetent donor CD4+ cells. Blood. 2003;101:2024-32 pubmed
Kim I, Koh C, Jeon I, Shin K, Kang T, Bae E, et al. GM-CSF Promotes Antitumor Immunity by Inducing Th9 Cell Responses. Cancer Immunol Res. 2019;7:498-509 pubmed publisher
Kandula S, Abraham C. LFA-1 on CD4+ T cells is required for optimal antigen-dependent activation in vivo. J Immunol. 2004;173:4443-51 pubmed
product information
Product Type :
Antibody
Product Name :
TCR DO11.10 Monoclonal Antibody (KJ1-26), PE
Catalog # :
MA5-17663
Quantity :
50 ug
Price :
US 371.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 ug/1x10^6 cells
Species :
Mouse
Clone :
KJ1-26
Isotype :
IgG2a
Storage :
4 C, do not freeze
Description :
TCR DO11 (DO11.10) is a receptor found on lymphocytes of DO11.10 transgenic mice and T-cell receptors of BALB/c-derived DO11.10 and DO11.10.24 T cell hybridomas. The DO11.10 TCR recognizes a C-terminal ovalbumin peptide (OVA 323-339) in the context of I-Ad major histocompatibility molecules. The use of antibodies against DO11.10 have proven to be instrumental in describing many of the intricate details of T cell immunity, including T cell activation, development, and function.
Immunogen :
T cell hybridoma, D011.10
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/1x10^6 cells
Aliases :
D011.10; T cell receptor alpha chain; Tcra; Tcralpha
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA