product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TCR DO11.10 Monoclonal Antibody (KJ1-26), FITC
catalog :
MA5-17662
quantity :
100 ug
price :
US 214.00
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
KJ1-26
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 26
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 5
Ding Z, Bergman A, Rutemark C, Ouchida R, Ohno H, Wang J, et al. Complement-activating IgM enhances the humoral but not the T cell immune response in mice. PLoS ONE. 2013;8:e81299 pubmed publisher
  • flow cytometry; mouse; fig 2
Tanaka S, Maeda S, Hashimoto M, Fujimori C, Ito Y, Teradaira S, et al. Graded attenuation of TCR signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function. J Immunol. 2010;185:2295-305 pubmed publisher
  • flow cytometry; mouse
Tsumiyama K, Miyazaki Y, Shiozawa S. Self-organized criticality theory of autoimmunity. PLoS ONE. 2009;4:e8382 pubmed publisher
  • flow cytometry; mouse; fig 1
Burbach B, Srivastava R, Medeiros R, O Gorman W, Peterson E, Shimizu Y. Distinct regulation of integrin-dependent T cell conjugate formation and NF-kappa B activation by the adapter protein ADAP. J Immunol. 2008;181:4840-51 pubmed
  • flow cytometry; mouse; fig 2a
Kanzato H, Fujiwara S, Ise W, Kaminogawa S, Sato R, Hachimura S. Lactobacillus acidophilus strain L-92 induces apoptosis of antigen-stimulated T cells by modulating dendritic cell function. Immunobiology. 2008;213:399-408 pubmed publisher
  • flow cytometry; mouse; fig 5
Watanabe T, Katsukura H, Chiba T, Kita T, Wakatsuki Y. Periportal and sinusoidal liver dendritic cells suppressing T helper type 1-mediated hepatitis. Gut. 2007;56:1445-51 pubmed
  • flow cytometry; mouse
Carlsson F, Hjelm F, Conrad D, Heyman B. IgE enhances specific antibody and T-cell responses in mice overexpressing CD23. Scand J Immunol. 2007;66:261-70 pubmed
  • flow cytometry; mouse
Ohshima Y, Yamada A, Tokuriki S, Yasutomi M, Omata N, Mayumi M. Transmaternal exposure to bisphenol a modulates the development of oral tolerance. Pediatr Res. 2007;62:60-4 pubmed
  • flow cytometry; mouse
Cao O, Dobrzynski E, Wang L, Nayak S, Mingle B, Terhorst C, et al. Induction and role of regulatory CD4+CD25+ T cells in tolerance to the transgene product following hepatic in vivo gene transfer. Blood. 2007;110:1132-40 pubmed
  • flow cytometry; mouse; fig 5
Hansen W, Loser K, Westendorf A, Bruder D, Pfoertner S, Siewert C, et al. G protein-coupled receptor 83 overexpression in naive CD4+CD25- T cells leads to the induction of Foxp3+ regulatory T cells in vivo. J Immunol. 2006;177:209-15 pubmed
  • flow cytometry; mouse
Jung Y, Schoeb T, Weaver C, Chaplin D. Antigen and lipopolysaccharide play synergistic roles in the effector phase of airway inflammation in mice. Am J Pathol. 2006;168:1425-34 pubmed
  • flow cytometry; mouse
Rasooly R, Schuster G, Gregg J, Xiao J, Chandraratna R, Stephensen C. Retinoid x receptor agonists increase bcl2a1 expression and decrease apoptosis of naive T lymphocytes. J Immunol. 2005;175:7916-29 pubmed
  • immunohistochemistry - frozen section; mouse; fig 2
Wang L, Dobrzynski E, Schlachterman A, Cao O, Herzog R. Systemic protein delivery by muscle-gene transfer is limited by a local immune response. Blood. 2005;105:4226-34 pubmed
  • flow cytometry; mouse
McRae B, Wallace C, Dixon K, Roux A, Mohan S, Jia Y, et al. Suppression of CD4+ T cell activation by a novel inhibitor of Src family kinases. Int Immunopharmacol. 2005;5:667-77 pubmed
  • flow cytometry; mouse; fig 1
Sparks Thissen R, Braaten D, Kreher S, Speck S, Virgin H. An optimized CD4 T-cell response can control productive and latent gammaherpesvirus infection. J Virol. 2004;78:6827-35 pubmed
  • flow cytometry; mouse
Barbey C, Donatelli Dufour N, Batard P, Corradin G, Spertini F. Intranasal treatment with ovalbumin but not the major T cell epitope ovalbumin 323-339 generates interleukin-10 secreting T cells and results in the induction of allergen systemic tolerance. Clin Exp Allergy. 2004;34:654-62 pubmed
  • flow cytometry; mouse
Yamori M, Yoshida M, Watanabe T, Shirai Y, Iizuka T, Kita T, et al. Antigenic activation of Th1 cells in the gastric mucosa enhances dysregulated apoptosis and turnover of the epithelial cells. Biochem Biophys Res Commun. 2004;316:1015-21 pubmed
  • flow cytometry; mouse; fig 3
Guo Z, Kavanagh E, Zang Y, Dolan S, Kriynovich S, Mannick J, et al. Burn injury promotes antigen-driven Th2-type responses in vivo. J Immunol. 2003;171:3983-90 pubmed
  • flow cytometry; mouse
Yamazaki S, Iyoda T, Tarbell K, Olson K, Velinzon K, Inaba K, et al. Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J Exp Med. 2003;198:235-47 pubmed
  • flow cytometry; mouse
Pape K, Kouskoff V, Nemazee D, Tang H, Cyster J, Tze L, et al. Visualization of the genesis and fate of isotype-switched B cells during a primary immune response. J Exp Med. 2003;197:1677-87 pubmed
  • flow cytometry; mouse
Reinhardt R, Bullard D, Weaver C, Jenkins M. Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation. J Exp Med. 2003;197:751-62 pubmed
  • flow cytometry; mouse; fig 1
Ingulli E, Ulman D, Lucido M, Jenkins M. In situ analysis reveals physical interactions between CD11b+ dendritic cells and antigen-specific CD4 T cells after subcutaneous injection of antigen. J Immunol. 2002;169:2247-52 pubmed
  • flow cytometry; mouse
Montoya M, Schiavoni G, Mattei F, Gresser I, Belardelli F, Borrow P, et al. Type I interferons produced by dendritic cells promote their phenotypic and functional activation. Blood. 2002;99:3263-71 pubmed
  • flow cytometry; mouse
Zell T, Khoruts A, Ingulli E, Bonnevier J, Mueller D, Jenkins M. Single-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivo. Proc Natl Acad Sci U S A. 2001;98:10805-10 pubmed
  • flow cytometry; mouse
Mathew A, MacLean J, DeHaan E, Tager A, Green F, Luster A. Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation. J Exp Med. 2001;193:1087-96 pubmed
  • flow cytometry; mouse; fig 11
Ben Sasson S, Makedonski K, Hu Li J, Paul W. Survival and cytokine polarization of naive CD4(+) T cells in vitro is largely dependent on exogenous cytokines. Eur J Immunol. 2000;30:1308-17 pubmed
product information
Product Type :
Antibody
Product Name :
TCR DO11.10 Monoclonal Antibody (KJ1-26), FITC
Catalog # :
MA5-17662
Quantity :
100 ug
Price :
US 214.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 ug/1x10^6 cells
Species :
Mouse
Clone :
KJ1-26
Isotype :
IgG2a
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles. Store in the dark.
Description :
TCR DO11 (DO11.10) is a receptor found on lymphocytes of DO11.10 transgenic mice and T-cell receptors of BALB/c-derived DO11.10 and DO11.10.24 T cell hybridomas. The DO11.10 TCR recognizes a C-terminal ovalbumin peptide (OVA 323-339) in the context of I-Ad major histocompatibility molecules. The use of antibodies against DO11.10 have proven to be instrumental in describing many of the intricate details of T cell immunity, including T cell activation, development, and function.
Immunogen :
T cell hybridoma, D011.10
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/1x10^6 cells
Aliases :
D011.10; T cell receptor alpha chain; Tcra; Tcralpha
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA