product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TCR DO11.10 Monoclonal Antibody (KJ1-26)
catalog :
MA5-17659
quantity :
200 ug
price :
US 500.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
KJ1-26
reactivity :
mouse, chicken
application :
ELISA, immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 144
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 1a
Chien C, Yu H, Chen S, Chiang B. Characterization of c-Maf+Foxp3- Regulatory T Cells Induced by Repeated Stimulation of Antigen-Presenting B Cells. Sci Rep. 2017;7:46348 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4l
Sujino T, London M, Hoytema van Konijnenburg D, Rendon T, Buch T, Silva H, et al. Tissue adaptation of regulatory and intraepithelial CD4? T cells controls gut inflammation. Science. 2016;352:1581-6 pubmed publisher
  • flow cytometry; mouse; fig 1
Wirsdörfer F, Bangen J, Pastille E, Hansen W, Flohé S. Breaking the co-operation between bystander T-cells and natural killer cells prevents the development of immunosuppression after traumatic skeletal muscle injury in mice. Clin Sci (Lond). 2015;128:825-38 pubmed publisher
  • flow cytometry; mouse; fig 5
Ding Z, Bergman A, Rutemark C, Ouchida R, Ohno H, Wang J, et al. Complement-activating IgM enhances the humoral but not the T cell immune response in mice. PLoS ONE. 2013;8:e81299 pubmed publisher
  • flow cytometry; mouse; fig 4
Weinstein J, Delano M, Xu Y, Kelly Scumpia K, Nacionales D, Li Y, et al. Maintenance of anti-Sm/RNP autoantibody production by plasma cells residing in ectopic lymphoid tissue and bone marrow memory B cells. J Immunol. 2013;190:3916-27 pubmed publisher
  • flow cytometry; mouse; fig 3
Wikstrom M, Batanero E, Judd S, Wiqvist K, Holt P, Stumbles P. Lung homing T-cell generation is dependent on strength and timing of antigen delivery to lymph nodes. Immunol Cell Biol. 2010;88:658-66 pubmed publisher
  • flow cytometry; mouse
Tsumiyama K, Miyazaki Y, Shiozawa S. Self-organized criticality theory of autoimmunity. PLoS ONE. 2009;4:e8382 pubmed publisher
  • flow cytometry; mouse
Bakocevic N, Worbs T, Davalos Misslitz A, Forster R. T cell-dendritic cell interaction dynamics during the induction of respiratory tolerance and immunity. J Immunol. 2010;184:1317-27 pubmed publisher
  • flow cytometry; mouse
Molenaar R, Greuter M, van der Marel A, Roozendaal R, Martin S, Edele F, et al. Lymph node stromal cells support dendritic cell-induced gut-homing of T cells. J Immunol. 2009;183:6395-402 pubmed publisher
  • flow cytometry; mouse
Getahun A, Heyman B. Studies on the mechanism by which antigen-specific IgG suppresses primary antibody responses: evidence for epitope masking and decreased localization of antigen in the spleen. Scand J Immunol. 2009;70:277-87 pubmed publisher
  • flow cytometry; mouse; fig 1
Jaffar Z, Ferrini M, Herritt L, Roberts K. Cutting edge: lung mucosal Th17-mediated responses induce polymeric Ig receptor expression by the airway epithelium and elevate secretory IgA levels. J Immunol. 2009;182:4507-11 pubmed publisher
  • flow cytometry; mouse
Sato K, Eizumi K, Fukaya T, Fujita S, Sato Y, Takagi H, et al. Naturally occurring regulatory dendritic cells regulate murine cutaneous chronic graft-versus-host disease. Blood. 2009;113:4780-9 pubmed publisher
  • flow cytometry; mouse
Costalonga M, Cleary P, Fischer L, Zhao Z. Intranasal bacteria induce Th1 but not Treg or Th2. Mucosal Immunol. 2009;2:85-95 pubmed publisher
  • flow cytometry; mouse
Hibi M, Hachimura S, Somaya T, Toda E, Hashiguchi M, Takayama T, et al. Splenic Dendritic Cells from Antigen-Fed Mice Induced Antigen-Specific T Cell Unresponsiveness in vivo. Cytotechnology. 2003;43:41-8 pubmed
  • flow cytometry; mouse
Saito K, Torii M, Ma N, Tsuchiya T, Wang L, Hori T, et al. Differential regulatory function of resting and preactivated allergen-specific CD4+ CD25+ regulatory T cells in Th2-type airway inflammation. J Immunol. 2008;181:6889-97 pubmed
  • flow cytometry; mouse; fig 4b
Van V, Darwiche J, Raymond M, Lesage S, Bouguermouh S, Rubio M, et al. Cutting edge: CD47 controls the in vivo proliferation and homeostasis of peripheral CD4+ CD25+ Foxp3+ regulatory T cells that express CD103. J Immunol. 2008;181:5204-8 pubmed
  • flow cytometry; mouse; fig 1
Burbach B, Srivastava R, Medeiros R, O Gorman W, Peterson E, Shimizu Y. Distinct regulation of integrin-dependent T cell conjugate formation and NF-kappa B activation by the adapter protein ADAP. J Immunol. 2008;181:4840-51 pubmed
  • flow cytometry; mouse; fig 1
Dalai S, Mirshahidi S, Morrot A, Zavala F, Sadegh Nasseri S. Anergy in memory CD4+ T cells is induced by B cells. J Immunol. 2008;181:3221-31 pubmed
  • flow cytometry; mouse; fig 1
Adeeku E, Gudapati P, Mendez Fernandez Y, Van Kaer L, Boothby M. Flexibility accompanies commitment of memory CD4 lymphocytes derived from IL-4 locus-activated precursors. Proc Natl Acad Sci U S A. 2008;105:9307-12 pubmed publisher
  • flow cytometry; mouse; fig 2a
Kanzato H, Fujiwara S, Ise W, Kaminogawa S, Sato R, Hachimura S. Lactobacillus acidophilus strain L-92 induces apoptosis of antigen-stimulated T cells by modulating dendritic cell function. Immunobiology. 2008;213:399-408 pubmed publisher
  • flow cytometry; mouse; fig 1
Robbins C, Franco F, Mouded M, Cernadas M, Shapiro S. Cigarette smoke exposure impairs dendritic cell maturation and T cell proliferation in thoracic lymph nodes of mice. J Immunol. 2008;180:6623-8 pubmed
  • flow cytometry; mouse
Reinwald S, Wiethe C, Westendorf A, Breloer M, Probst Kepper M, Fleischer B, et al. CD83 expression in CD4+ T cells modulates inflammation and autoimmunity. J Immunol. 2008;180:5890-7 pubmed
  • flow cytometry; mouse; fig 1d
Bommireddy R, Babcock G, Singh R, Doetschman T. TGFbeta1 deficiency does not affect the generation and maintenance of CD4+CD25+FOXP3+ putative Treg cells, but causes their numerical inadequacy and loss of regulatory function. Clin Immunol. 2008;127:206-13 pubmed publisher
  • flow cytometry; mouse; fig 5
Barron L, Knoechel B, Lohr J, Abbas A. Cutting edge: contributions of apoptosis and anergy to systemic T cell tolerance. J Immunol. 2008;180:2762-6 pubmed
  • flow cytometry; mouse; fig 3
King S, Knorn A, Ohnmacht C, Voehringer D. Accumulation of effector CD4 T cells during type 2 immune responses is negatively regulated by Stat6. J Immunol. 2008;180:754-63 pubmed
  • flow cytometry; mouse
Gorman S, Kuritzky L, Judge M, Dixon K, McGlade J, Mason R, et al. Topically applied 1,25-dihydroxyvitamin D3 enhances the suppressive activity of CD4+CD25+ cells in the draining lymph nodes. J Immunol. 2007;179:6273-83 pubmed
  • flow cytometry; mouse
von Garnier C, Wikstrom M, Zosky G, Turner D, Sly P, Smith M, et al. Allergic airways disease develops after an increase in allergen capture and processing in the airway mucosa. J Immunol. 2007;179:5748-59 pubmed
  • flow cytometry; mouse
Park S, Han Y, Aleyas A, George J, Yoon H, Lee J, et al. Low-dose antigen-experienced CD4+ T cells display reduced clonal expansion but facilitate an effective memory pool in response to secondary exposure. Immunology. 2008;123:426-37 pubmed
  • flow cytometry; mouse; fig 5
Watanabe T, Katsukura H, Chiba T, Kita T, Wakatsuki Y. Periportal and sinusoidal liver dendritic cells suppressing T helper type 1-mediated hepatitis. Gut. 2007;56:1445-51 pubmed
  • flow cytometry; mouse; fig 3
Manni M, Maestroni G. Sympathetic nervous modulation of the skin innate and adaptive immune response to peptidoglycan but not lipopolysaccharide: involvement of beta-adrenoceptors and relevance in inflammatory diseases. Brain Behav Immun. 2008;22:80-8 pubmed
  • flow cytometry; mouse
Mody P, Cannon J, Bandukwala H, Blaine K, Schilling A, Swier K, et al. Signaling through CD43 regulates CD4 T-cell trafficking. Blood. 2007;110:2974-82 pubmed
  • flow cytometry; mouse
  • immunohistochemistry; mouse
Carlsson F, Hjelm F, Conrad D, Heyman B. IgE enhances specific antibody and T-cell responses in mice overexpressing CD23. Scand J Immunol. 2007;66:261-70 pubmed
  • flow cytometry; mouse
van der Marel A, Samsom J, Greuter M, van Berkel L, O Toole T, Kraal G, et al. Blockade of IDO inhibits nasal tolerance induction. J Immunol. 2007;179:894-900 pubmed
  • flow cytometry; mouse
Ohshima Y, Yamada A, Tokuriki S, Yasutomi M, Omata N, Mayumi M. Transmaternal exposure to bisphenol a modulates the development of oral tolerance. Pediatr Res. 2007;62:60-4 pubmed
  • flow cytometry; chicken; fig 4
Sinha P, Clements V, Fulton A, Ostrand Rosenberg S. Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells. Cancer Res. 2007;67:4507-13 pubmed
  • flow cytometry; mouse
Desai D, Harbers S, Flores M, Colonna L, Downie M, Bergtold A, et al. Fc gamma receptor IIB on dendritic cells enforces peripheral tolerance by inhibiting effector T cell responses. J Immunol. 2007;178:6217-26 pubmed
  • flow cytometry; mouse
Sengupta S, Jayaraman P, Chilton P, Casella C, Mitchell T. Unrestrained glycogen synthase kinase-3 beta activity leads to activated T cell death and can be inhibited by natural adjuvant. J Immunol. 2007;178:6083-91 pubmed
  • flow cytometry; mouse
Boogaard I, van Oosten M, van Rijt L, Muskens F, Kimman T, Lambrecht B, et al. Respiratory syncytial virus differentially activates murine myeloid and plasmacytoid dendritic cells. Immunology. 2007;122:65-72 pubmed
  • flow cytometry; mouse
Burster T, Giffon T, Dahl M, Björck P, Bogyo M, Weber E, et al. Influenza A virus elevates active cathepsin B in primary murine DC. Int Immunol. 2007;19:645-55 pubmed
  • flow cytometry; mouse
Arredouani M, Franco F, Imrich A, Fedulov A, Lu X, Perkins D, et al. Scavenger Receptors SR-AI/II and MARCO limit pulmonary dendritic cell migration and allergic airway inflammation. J Immunol. 2007;178:5912-20 pubmed
  • flow cytometry; mouse
Cao O, Dobrzynski E, Wang L, Nayak S, Mingle B, Terhorst C, et al. Induction and role of regulatory CD4+CD25+ T cells in tolerance to the transgene product following hepatic in vivo gene transfer. Blood. 2007;110:1132-40 pubmed
  • immunohistochemistry; mouse; fig 1
Reichardt P, Dornbach B, Rong S, Beissert S, Gueler F, Loser K, et al. Naive B cells generate regulatory T cells in the presence of a mature immunologic synapse. Blood. 2007;110:1519-29 pubmed
  • flow cytometry; mouse
Yamamoto T, Hattori M, Yoshida T. Induction of T-cell activation or anergy determined by the combination of intensity and duration of T-cell receptor stimulation, and sequential induction in an individual cell. Immunology. 2007;121:383-91 pubmed
  • flow cytometry; mouse
Ling K, van Hamburg J, de Bruijn M, Kurek D, Dingjan G, Hendriks R. GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development. Eur J Immunol. 2007;37:1043-52 pubmed
  • flow cytometry; mouse; fig 2A
MacKenzie D, Schartner J, Lin J, Timmel A, Jennens Clough M, Fathman C, et al. GRAIL is up-regulated in CD4+ CD25+ T regulatory cells and is sufficient for conversion of T cells to a regulatory phenotype. J Biol Chem. 2007;282:9696-702 pubmed
  • flow cytometry; mouse
Ebihara M, Hattori M, Yoshida T. Distinctly different sensitivity in the induction and reversal of anergy of Th1 and Th2 cells. Biosci Biotechnol Biochem. 2007;71:130-7 pubmed
  • flow cytometry; mouse
Tse H, Milton M, Schreiner S, Profozich J, Trucco M, Piganelli J. Disruption of innate-mediated proinflammatory cytokine and reactive oxygen species third signal leads to antigen-specific hyporesponsiveness. J Immunol. 2007;178:908-17 pubmed
  • flow cytometry; mouse
Hamdy S, Elamanchili P, Alshamsan A, Molavi O, Satou T, Samuel J. Enhanced antigen-specific primary CD4+ and CD8+ responses by codelivery of ovalbumin and toll-like receptor ligand monophosphoryl lipid A in poly(D,L-lactic-co-glycolic acid) nanoparticles. J Biomed Mater Res A. 2007;81:652-62 pubmed
  • flow cytometry; mouse
Wang Z, Davies J. CD8 blockade promotes the expansion of antigen-specific CD4+ FOXP3+ regulatory T cells in vivo. Int Immunopharmacol. 2007;7:249-65 pubmed
  • flow cytometry; mouse; fig 6
Rothoeft T, Balkow S, Krummen M, Beissert S, Varga G, Loser K, et al. Structure and duration of contact between dendritic cells and T cells are controlled by T cell activation state. Eur J Immunol. 2006;36:3105-17 pubmed
  • flow cytometry; mouse; fig 2
Okkenhaug K, Patton D, Bilancio A, Garcon F, Rowan W, Vanhaesebroeck B. The p110delta isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells. J Immunol. 2006;177:5122-8 pubmed
  • flow cytometry; mouse; fig 2
Coleman C, Howell K, Hobbs M, Riggs J. Age-dependent loss of naïve T cells in TCR transgenic bone marrow chimeras. Immunobiology. 2006;211:701-9 pubmed
  • flow cytometry; mouse
Kuipers H, Muskens F, Willart M, Hijdra D, van Assema F, Coyle A, et al. Contribution of the PD-1 ligands/PD-1 signaling pathway to dendritic cell-mediated CD4+ T cell activation. Eur J Immunol. 2006;36:2472-82 pubmed
  • flow cytometry; mouse; fig 1
Gray P, Reiner S, Smith D, Kaye P, Scott P. Antigen-experienced T cells limit the priming of naive T cells during infection with Leishmania major. J Immunol. 2006;177:925-33 pubmed
  • flow cytometry; mouse
Wikstrom M, Batanero E, Smith M, Thomas J, von Garnier C, Holt P, et al. Influence of mucosal adjuvants on antigen passage and CD4+ T cell activation during the primary response to airborne allergen. J Immunol. 2006;177:913-24 pubmed
  • flow cytometry; mouse
Moulton V, Bushar N, Leeser D, Patke D, Farber D. Divergent generation of heterogeneous memory CD4 T cells. J Immunol. 2006;177:869-76 pubmed
  • flow cytometry; mouse; fig 5
Hansen W, Loser K, Westendorf A, Bruder D, Pfoertner S, Siewert C, et al. G protein-coupled receptor 83 overexpression in naive CD4+CD25- T cells leads to the induction of Foxp3+ regulatory T cells in vivo. J Immunol. 2006;177:209-15 pubmed
  • flow cytometry; mouse
Hubeau C, Apostolou I, Kobzik L. Adoptively transferred allergen-specific T cells cause maternal transmission of asthma risk. Am J Pathol. 2006;168:1931-9 pubmed
  • flow cytometry; mouse
Knoechel B, Lohr J, Zhu S, Wong L, Hu D, Ausubel L, et al. Functional and molecular comparison of anergic and regulatory T lymphocytes. J Immunol. 2006;176:6473-83 pubmed
  • flow cytometry; mouse
Vanasek T, Nandiwada S, Jenkins M, Mueller D. CD25+Foxp3+ regulatory T cells facilitate CD4+ T cell clonal anergy induction during the recovery from lymphopenia. J Immunol. 2006;176:5880-9 pubmed
  • flow cytometry; mouse
Jung Y, Schoeb T, Weaver C, Chaplin D. Antigen and lipopolysaccharide play synergistic roles in the effector phase of airway inflammation in mice. Am J Pathol. 2006;168:1425-34 pubmed
  • flow cytometry; mouse
Berenson L, Yang J, Sleckman B, Murphy T, Murphy K. Selective requirement of p38alpha MAPK in cytokine-dependent, but not antigen receptor-dependent, Th1 responses. J Immunol. 2006;176:4616-21 pubmed
  • flow cytometry; mouse
Worbs T, Bode U, Yan S, Hoffmann M, Hintzen G, Bernhardt G, et al. Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells. J Exp Med. 2006;203:519-27 pubmed
  • flow cytometry; mouse
Foulds K, Shen H. Clonal competition inhibits the proliferation and differentiation of adoptively transferred TCR transgenic CD4 T cells in response to infection. J Immunol. 2006;176:3037-43 pubmed
  • flow cytometry; mouse; fig 5
Jang M, Sougawa N, Tanaka T, Hirata T, Hiroi T, Tohya K, et al. CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes. J Immunol. 2006;176:803-10 pubmed
  • flow cytometry; mouse
Rasooly R, Schuster G, Gregg J, Xiao J, Chandraratna R, Stephensen C. Retinoid x receptor agonists increase bcl2a1 expression and decrease apoptosis of naive T lymphocytes. J Immunol. 2005;175:7916-29 pubmed
  • flow cytometry; mouse
Marski M, Kandula S, Turner J, Abraham C. CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells. J Immunol. 2005;175:7889-97 pubmed
  • flow cytometry; mouse
Thompson B, Chilton P, Ward J, Evans J, Mitchell T. The low-toxicity versions of LPS, MPL adjuvant and RC529, are efficient adjuvants for CD4+ T cells. J Leukoc Biol. 2005;78:1273-80 pubmed
  • flow cytometry; mouse
Sangaletti S, Gioiosa L, Guiducci C, Rotta G, Rescigno M, Stoppacciaro A, et al. Accelerated dendritic-cell migration and T-cell priming in SPARC-deficient mice. J Cell Sci. 2005;118:3685-94 pubmed
  • flow cytometry; mouse
von Garnier C, Filgueira L, Wikstrom M, Smith M, Thomas J, Strickland D, et al. Anatomical location determines the distribution and function of dendritic cells and other APCs in the respiratory tract. J Immunol. 2005;175:1609-18 pubmed
  • flow cytometry; mouse
Getahun A, Hjelm F, Heyman B. IgE enhances antibody and T cell responses in vivo via CD23+ B cells. J Immunol. 2005;175:1473-82 pubmed
  • flow cytometry; mouse
DeRyckere D, DeGregori J. E2F1 and E2F2 are differentially required for homeostasis-driven and antigen-induced T cell proliferation in vivo. J Immunol. 2005;175:647-55 pubmed
  • flow cytometry; mouse
Wille Reece U, Wu C, Flynn B, Kedl R, Seder R. Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses. J Immunol. 2005;174:7676-83 pubmed
  • flow cytometry; mouse
Gorman S, Tan J, Thomas J, Townley S, Stumbles P, Finlay Jones J, et al. Primary defect in UVB-induced systemic immunomodulation does not relate to immature or functionally impaired APCs in regional lymph nodes. J Immunol. 2005;174:6677-85 pubmed
  • flow cytometry; mouse; fig 1
Hardtke S, Ohl L, Forster R. Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help. Blood. 2005;106:1924-31 pubmed
  • flow cytometry; mouse; fig 2
Shin T, Yoshimura K, Shin T, Crafton E, Tsuchiya H, Housseau F, et al. In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses. J Exp Med. 2005;201:1531-41 pubmed
  • flow cytometry; mouse; fig 4
Cruise M, Melief H, Lukens J, Soguero C, Hahn Y. Increased Fas ligand expression of CD4+ T cells by HCV core induces T cell-dependent hepatic inflammation. J Leukoc Biol. 2005;78:412-25 pubmed
  • flow cytometry; mouse; fig 4
Minami K, Yanagawa Y, Iwabuchi K, Shinohara N, Harabayashi T, Nonomura K, et al. Negative feedback regulation of T helper type 1 (Th1)/Th2 cytokine balance via dendritic cell and natural killer T cell interactions. Blood. 2005;106:1685-93 pubmed
  • flow cytometry; mouse
Sato K, Tateishi S, Kubo K, Mimura T, Yamamoto K, Kanda H. Downregulation of IL-12 and a novel negative feedback system mediated by CD25+CD4+ T cells. Biochem Biophys Res Commun. 2005;330:226-32 pubmed
  • immunohistochemistry - frozen section; mouse; fig 2
  • flow cytometry; mouse
Wang L, Dobrzynski E, Schlachterman A, Cao O, Herzog R. Systemic protein delivery by muscle-gene transfer is limited by a local immune response. Blood. 2005;105:4226-34 pubmed
  • flow cytometry; mouse
McRae B, Wallace C, Dixon K, Roux A, Mohan S, Jia Y, et al. Suppression of CD4+ T cell activation by a novel inhibitor of Src family kinases. Int Immunopharmacol. 2005;5:667-77 pubmed
  • flow cytometry; mouse; fig 2
Hammad H, de Vries V, Maldonado Lopez R, Moser M, Maliszewski C, Hoogsteden H, et al. Differential capacity of CD8+ alpha or CD8- alpha dendritic cell subsets to prime for eosinophilic airway inflammation in the T-helper type 2-prone milieu of the lung. Clin Exp Allergy. 2004;34:1834-40 pubmed
  • flow cytometry; mouse; fig 4
Yasumi T, Katamura K, Okafuji I, Yoshioka T, Meguro T, Nishikomori R, et al. Limited ability of antigen-specific Th1 responses to inhibit Th2 cell development in vivo. J Immunol. 2005;174:1325-31 pubmed
  • flow cytometry; mouse; fig 1
Thompson B, Mitchell T. Measurement of daughter cell accumulation during lymphocyte proliferation in vivo. J Immunol Methods. 2004;295:79-87 pubmed
  • flow cytometry; mouse
Chun T, Byun H, Chung H, Chung Y. The effect of soluble LAG-3 (CD223) treatment in fetal thymic organ culture. Biotechnol Lett. 2004;26:1371-7 pubmed
  • flow cytometry; mouse; fig 5
Yu M, Chen C, Liang X, Wang L, Gandhi C, Fung J, et al. Inhibition of T-cell responses by hepatic stellate cells via B7-H1-mediated T-cell apoptosis in mice. Hepatology. 2004;40:1312-21 pubmed
  • flow cytometry; mouse
MartIn Fontecha A, Thomsen L, Brett S, Gerard C, Lipp M, Lanzavecchia A, et al. Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming. Nat Immunol. 2004;5:1260-5 pubmed
  • flow cytometry; mouse; fig 8
Miller M, Safrina O, Parker I, Cahalan M. Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes. J Exp Med. 2004;200:847-56 pubmed
  • flow cytometry; mouse; fig 2
Stephensen C, Jiang X, Freytag T. Vitamin A deficiency increases the in vivo development of IL-10-positive Th2 cells and decreases development of Th1 cells in mice. J Nutr. 2004;134:2660-6 pubmed
  • flow cytometry; mouse
Kandula S, Abraham C. LFA-1 on CD4+ T cells is required for optimal antigen-dependent activation in vivo. J Immunol. 2004;173:4443-51 pubmed
  • flow cytometry; mouse
Park H, Costalonga M, Reinhardt R, Dombek P, Jenkins M, Cleary P. Primary induction of CD4 T cell responses in nasal associated lymphoid tissue during group A streptococcal infection. Eur J Immunol. 2004;34:2843-53 pubmed
  • flow cytometry; mouse
Hagen K, Moses C, Drasler E, Podetz Pedersen K, Jameson S, Khoruts A. A role for CD28 in lymphopenia-induced proliferation of CD4 T cells. J Immunol. 2004;173:3909-15 pubmed
  • flow cytometry; mouse; fig 1
Kuipers H, Heirman C, Hijdra D, Muskens F, Willart M, Van Meirvenne S, et al. Dendritic cells retrovirally overexpressing IL-12 induce strong Th1 responses to inhaled antigen in the lung but fail to revert established Th2 sensitization. J Leukoc Biol. 2004;76:1028-38 pubmed
  • flow cytometry; mouse
van Rijt L, Vos N, Willart M, Kleinjan A, Coyle A, Hoogsteden H, et al. Essential role of dendritic cell CD80/CD86 costimulation in the induction, but not reactivation, of TH2 effector responses in a mouse model of asthma. J Allergy Clin Immunol. 2004;114:166-73 pubmed
  • flow cytometry; mouse
Turner J, Dobos K, Keen M, Frank A, Ehlers S, Orme I, et al. A limited antigen-specific cellular response is sufficient for the early control of Mycobacterium tuberculosis in the lung but is insufficient for long-term survival. Infect Immun. 2004;72:3759-68 pubmed
  • flow cytometry; mouse
Kimzey S, Liu P, Green J. Requirement for CD28 in the effector phase of allergic airway inflammation. J Immunol. 2004;173:632-40 pubmed
  • flow cytometry; mouse; fig 1
Seroogy C, Soares L, Ranheim E, Su L, Holness C, Bloom D, et al. The gene related to anergy in lymphocytes, an E3 ubiquitin ligase, is necessary for anergy induction in CD4 T cells. J Immunol. 2004;173:79-85 pubmed
  • flow cytometry; mouse; fig 1
Sparks Thissen R, Braaten D, Kreher S, Speck S, Virgin H. An optimized CD4 T-cell response can control productive and latent gammaherpesvirus infection. J Virol. 2004;78:6827-35 pubmed
  • flow cytometry; mouse; fig 3
Dobrzynski E, Mingozzi F, Liu Y, Bendo E, Cao O, Wang L, et al. Induction of antigen-specific CD4+ T-cell anergy and deletion by in vivo viral gene transfer. Blood. 2004;104:969-77 pubmed
  • flow cytometry; mouse; fig 1
Getahun A, Dahlstrom J, Wernersson S, Heyman B. IgG2a-mediated enhancement of antibody and T cell responses and its relation to inhibitory and activating Fc gamma receptors. J Immunol. 2004;172:5269-76 pubmed
  • flow cytometry; mouse
Barbey C, Donatelli Dufour N, Batard P, Corradin G, Spertini F. Intranasal treatment with ovalbumin but not the major T cell epitope ovalbumin 323-339 generates interleukin-10 secreting T cells and results in the induction of allergen systemic tolerance. Clin Exp Allergy. 2004;34:654-62 pubmed
  • immunohistochemistry - frozen section; mouse; fig 1
  • flow cytometry; mouse
Yamori M, Yoshida M, Watanabe T, Shirai Y, Iizuka T, Kita T, et al. Antigenic activation of Th1 cells in the gastric mucosa enhances dysregulated apoptosis and turnover of the epithelial cells. Biochem Biophys Res Commun. 2004;316:1015-21 pubmed
  • flow cytometry; mouse; fig 2
Angeli V, Staumont D, Charbonnier A, Hammad H, Gosset P, Pichavant M, et al. Activation of the D prostanoid receptor 1 regulates immune and skin allergic responses. J Immunol. 2004;172:3822-9 pubmed
  • flow cytometry; mouse; fig 5, 6
Richards D, Dalheimer S, Ehst B, Vanasek T, Jenkins M, Hertz M, et al. Indirect minor histocompatibility antigen presentation by allograft recipient cells in the draining lymph node leads to the activation and clonal expansion of CD4+ T cells that cause obliterative airways disease. J Immunol. 2004;172:3469-79 pubmed
  • ELISA; mouse; fig 5
Dahl M, Dabbagh K, Liggitt D, Kim S, Lewis D. Viral-induced T helper type 1 responses enhance allergic disease by effects on lung dendritic cells. Nat Immunol. 2004;5:337-43 pubmed
  • flow cytometry; mouse; fig 4
Perry J, Rush A, Wilson R, Olver C, Avery A. Dendritic cells from malaria-infected mice are fully functional APC. J Immunol. 2004;172:475-82 pubmed
  • flow cytometry; mouse; fig 4
Hammad H, de Heer H, Soullie T, Hoogsteden H, Trottein F, Lambrecht B. Prostaglandin D2 inhibits airway dendritic cell migration and function in steady state conditions by selective activation of the D prostanoid receptor 1. J Immunol. 2003;171:3936-40 pubmed
  • flow cytometry; mouse; fig 4
Lee H, Nam K, Seo S, Kim Y, Kang H, Kwon B. 4-1BB cross-linking enhances the survival and cell cycle progression of CD4 T lymphocytes. Cell Immunol. 2003;223:143-50 pubmed
  • flow cytometry; mouse
Mueller C, Weaver V, Vanden Heuvel J, August A, Cantorna M. Peroxisome proliferator-activated receptor gamma ligands attenuate immunological symptoms of experimental allergic asthma. Arch Biochem Biophys. 2003;418:186-96 pubmed
  • flow cytometry; mouse; fig 4
Kuipers H, Hijdra D, de Vries V, Hammad H, Prins J, Coyle A, et al. Lipopolysaccharide-induced suppression of airway Th2 responses does not require IL-12 production by dendritic cells. J Immunol. 2003;171:3645-54 pubmed
  • ELISA; mouse; fig 5
Matsue H, Edelbaum D, Shalhevet D, Mizumoto N, Yang C, Mummert M, et al. Generation and function of reactive oxygen species in dendritic cells during antigen presentation. J Immunol. 2003;171:3010-8 pubmed
  • ELISA; mouse; fig 4
Iwai H, Abe M, Hirose S, Tsushima F, Tezuka K, Akiba H, et al. Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis. J Immunol. 2003;171:2848-54 pubmed
  • flow cytometry; mouse; fig 7
Haeryfar S, Al Alwan M, Mader J, Rowden G, West K, Hoskin D. Thy-1 signaling in the context of costimulation provided by dendritic cells provides signal 1 for T cell proliferation and cytotoxic effector molecule expression, but fails to trigger delivery of the lethal hit. J Immunol. 2003;171:69-77 pubmed
  • flow cytometry; mouse
Pape K, Kouskoff V, Nemazee D, Tang H, Cyster J, Tze L, et al. Visualization of the genesis and fate of isotype-switched B cells during a primary immune response. J Exp Med. 2003;197:1677-87 pubmed
  • flow cytometry; mouse; fig 5
Angeli V, Hammad H, Staels B, Capron M, Lambrecht B, Trottein F. Peroxisome proliferator-activated receptor gamma inhibits the migration of dendritic cells: consequences for the immune response. J Immunol. 2003;170:5295-301 pubmed
  • flow cytometry; mouse
Reinhardt R, Bullard D, Weaver C, Jenkins M. Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation. J Exp Med. 2003;197:751-62 pubmed
  • flow cytometry; mouse
Tsang J, Chai J, Lechler R. Antigen presentation by mouse CD4+ T cells involving acquired MHC class II:peptide complexes: another mechanism to limit clonal expansion?. Blood. 2003;101:2704-10 pubmed
  • flow cytometry; mouse; fig 1
Matsue H, Yang C, Matsue K, Edelbaum D, Mummert M, Takashima A. Contrasting impacts of immunosuppressive agents (rapamycin, FK506, cyclosporin A, and dexamethasone) on bidirectional dendritic cell-T cell interaction during antigen presentation. J Immunol. 2002;169:3555-64 pubmed
  • flow cytometry; mouse
Furtado G, Curotto de Lafaille M, Kutchukhidze N, Lafaille J. Interleukin 2 signaling is required for CD4(+) regulatory T cell function. J Exp Med. 2002;196:851-7 pubmed
  • flow cytometry; mouse
Schrum A, Turka L. The proliferative capacity of individual naive CD4(+) T cells is amplified by prolonged T cell antigen receptor triggering. J Exp Med. 2002;196:793-803 pubmed
  • flow cytometry; mouse; fig 1
Ingulli E, Ulman D, Lucido M, Jenkins M. In situ analysis reveals physical interactions between CD11b+ dendritic cells and antigen-specific CD4 T cells after subcutaneous injection of antigen. J Immunol. 2002;169:2247-52 pubmed
  • flow cytometry; mouse
Chen Y, Ma Y, Chen Y. Roles of cytotoxic T-lymphocyte-associated antigen-4 in the inductive phase of oral tolerance. Immunology. 2002;105:171-80 pubmed
  • flow cytometry; mouse; fig 1
Gudmundsdottir H, Turka L. A closer look at homeostatic proliferation of CD4+ T cells: costimulatory requirements and role in memory formation. J Immunol. 2001;167:3699-707 pubmed
  • flow cytometry; mouse; fig 4
Campbell D, Kim C, Butcher E. Separable effector T cell populations specialized for B cell help or tissue inflammation. Nat Immunol. 2001;2:876-81 pubmed
  • flow cytometry; mouse; fig 3
Shi H, Liu H, Nagler Anderson C. Enteric infection acts as an adjuvant for the response to a model food antigen. J Immunol. 2000;165:6174-82 pubmed
  • flow cytometry; mouse
Olivares Villagómez D, Wensky A, Wang Y, Lafaille J. Repertoire requirements of CD4+ T cells that prevent spontaneous autoimmune encephalomyelitis. J Immunol. 2000;164:5499-507 pubmed
  • flow cytometry; mouse; fig 1
Iwabuchi K, Nakayama K, McCoy R, Wang F, Nishimura T, Habu S, et al. Cellular and peptide requirements for in vitro clonal deletion of immature thymocytes. Proc Natl Acad Sci U S A. 1992;89:9000-4 pubmed
  • flow cytometry; mouse; fig 1
Hsieh C, Heimberger A, Gold J, O GARRA A, Murphy K. Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. Proc Natl Acad Sci U S A. 1992;89:6065-9 pubmed
Uto T, Takagi H, Fukaya T, Nasu J, Fukui T, Miyanaga N, et al. Critical role of plasmacytoid dendritic cells in induction of oral tolerance. J Allergy Clin Immunol. 2018;141:2156-2167.e9 pubmed publisher
Attridge K, Kenefeck R, Wardzinski L, Qureshi O, Wang C, Manzotti C, et al. IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells. J Immunol. 2014;192:2195-201 pubmed publisher
Smigiel K, Richards E, Srivastava S, Thomas K, Dudda J, Klonowski K, et al. CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets. J Exp Med. 2014;211:121-36 pubmed publisher
Sapoznikov A, Fischer J, Zaft T, Krauthgamer R, Dzionek A, Jung S. Organ-dependent in vivo priming of naive CD4+, but not CD8+, T cells by plasmacytoid dendritic cells. J Exp Med. 2007;204:1923-33 pubmed
Coombes J, Siddiqui K, Arancibia Cárcamo C, Hall J, Sun C, Belkaid Y, et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med. 2007;204:1757-64 pubmed
Sather B, Treuting P, Perdue N, Miazgowicz M, Fontenot J, Rudensky A, et al. Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory disease. J Exp Med. 2007;204:1335-47 pubmed
Schneider M, Meingassner J, Lipp M, Moore H, Rot A. CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells. J Exp Med. 2007;204:735-45 pubmed
Lohr J, Knoechel B, Wang J, Villarino A, Abbas A. Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease. J Exp Med. 2006;203:2785-91 pubmed
Liang S, Tan X, Luxenberg D, Karim R, Dunussi Joannopoulos K, Collins M, et al. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med. 2006;203:2271-9 pubmed
Kearley J, Barker J, Robinson D, Lloyd C. Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+CD25+ regulatory T cells is interleukin 10 dependent. J Exp Med. 2005;202:1539-47 pubmed
Knoechel B, Lohr J, Kahn E, Bluestone J, Abbas A. Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen. J Exp Med. 2005;202:1375-86 pubmed
Eggena M, Walker L, Nagabhushanam V, Barron L, Chodos A, Abbas A. Cooperative roles of CTLA-4 and regulatory T cells in tolerance to an islet cell antigen. J Exp Med. 2004;199:1725-30 pubmed
Wang N, Satoskar A, Faubion W, Howie D, Okamoto S, Feske S, et al. The cell surface receptor SLAM controls T cell and macrophage functions. J Exp Med. 2004;199:1255-64 pubmed
Sugimoto T, Ishikawa Y, Yoshimoto T, Hayashi N, Fujimoto J, Nakanishi K. Interleukin 18 acts on memory T helper cells type 1 to induce airway inflammation and hyperresponsiveness in a naive host mouse. J Exp Med. 2004;199:535-45 pubmed
Walker L, Chodos A, Eggena M, Dooms H, Abbas A. Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo. J Exp Med. 2003;198:249-58 pubmed
Yamazaki S, Iyoda T, Tarbell K, Olson K, Velinzon K, Inaba K, et al. Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J Exp Med. 2003;198:235-47 pubmed
product information
Product Type :
Antibody
Product Name :
TCR DO11.10 Monoclonal Antibody (KJ1-26)
Catalog # :
MA5-17659
Quantity :
200 ug
Price :
US 500.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 ug/1x10^6 cells
Species :
Mouse
Clone :
KJ1-26
Isotype :
IgG2a
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
TCR DO11 (DO11.10) is a receptor found on lymphocytes of DO11.10 transgenic mice and T-cell receptors of BALB/c-derived DO11.10 and DO11.10.24 T cell hybridomas. The DO11.10 TCR recognizes a C-terminal ovalbumin peptide (OVA 323-339) in the context of I-Ad major histocompatibility molecules. The use of antibodies against DO11.10 have proven to be instrumental in describing many of the intricate details of T cell immunity, including T cell activation, development, and function.
Immunogen :
T cell hybridoma, D011.10
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/1x10^6 cells
Aliases :
D011.10; T cell receptor alpha chain; Tcra; Tcralpha
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA