TCR beta Monoclonal Antibody (H57-597), FITC | Invitrogen MA5-17652 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TCR beta Monoclonal Antibody (H57-597), FITC

catalog :

MA5-17652

quantity :

300 ug

price :

US 371.00

clonality :

monoclonal

host :

hamsters

conjugate :

FITC

clone name :

H57-597

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 6A	Veinotte L, Gebremeskel S, Johnston B. CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFN? production and tumor control. Oncoimmunology. 2016;5:e1160979 pubmed publisher
flow cytometry; mouse; fig 5	Kanwar N, Fayyazi A, Backofen B, Nitsche M, Dressel R, von Mollard G. Thymic alterations in mice deficient for the SNARE protein VAMP8/endobrevin. Cell Tissue Res. 2008;334:227-42 pubmed publisher
flow cytometry; mouse; fig 1	Woolard M, Hensley L, Kawula T, Frelinger J. Respiratory Francisella tularensis live vaccine strain infection induces Th17 cells and prostaglandin E2, which inhibits generation of gamma interferon-positive T cells. Infect Immun. 2008;76:2651-9 pubmed publisher
flow cytometry; mouse	Zhang T, He X, Tsang T, Harris D. Transgenic TCR expression: comparison of single chain with full-length receptor constructs for T-cell function. Cancer Gene Ther. 2004;11:487-96 pubmed
flow cytometry; mouse	Angulo I, Jiménez Díaz M, García Bustos J, Gargallo D, de las Heras F, Muñoz Fernández M, et al. Candida albicans infection enhances immunosuppression induced by cyclophosphamide by selective priming of suppressive myeloid progenitors for NO production. Cell Immunol. 2002;218:46-58 pubmed
flow cytometry; mouse	Hsu S, Wu C, Han J, Lai M. Involvement of p38 mitogen-activated protein kinase in different stages of thymocyte development. Blood. 2003;101:970-6 pubmed
flow cytometry; mouse	Yu C, Feng M, Shih H, Lai M. Increased p300 expression inhibits glucocorticoid receptor-T-cell receptor antagonism but does not affect thymocyte positive selection. Mol Cell Biol. 2002;22:4556-66 pubmed
flow cytometry; mouse; fig 1	Walzer T, Arpin C, Beloeil L, Marvel J. Differential in vivo persistence of two subsets of memory phenotype CD8 T cells defined by CD44 and CD122 expression levels. J Immunol. 2002;168:2704-11 pubmed
flow cytometry; mouse; fig 3, 4	Leite De Moraes M, Hameg A, Pacilio M, Koezuka Y, Taniguchi M, van Kaer L, et al. IL-18 enhances IL-4 production by ligand-activated NKT lymphocytes: a pro-Th2 effect of IL-18 exerted through NKT cells. J Immunol. 2001;166:945-51 pubmed
flow cytometry; mouse	Egan P, Carding S. Downmodulation of the inflammatory response to bacterial infection by gammadelta T cells cytotoxic for activated macrophages. J Exp Med. 2000;191:2145-58 pubmed
flow cytometry; mouse	Angulo I, de las Heras F, Garcia Bustos J, Gargallo D, Munoz Fernandez M, Fresno M. Nitric oxide-producing CD11b(+)Ly-6G(Gr-1)(+)CD31(ER-MP12)(+) cells in the spleen of cyclophosphamide-treated mice: implications for T-cell responses in immunosuppressed mice. Blood. 2000;95:212-20 pubmed
flow cytometry; mouse	Dejbakhsh Jones S, Strober S. Identification of an early T cell progenitor for a pathway of T cell maturation in the bone marrow. Proc Natl Acad Sci U S A. 1999;96:14493-8 pubmed
	Jandl C, Liu S, Canete P, Warren J, Hughes W, Vogelzang A, et al. IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2. Nat Commun. 2017;8:14647 pubmed publisher
	Goubier A, Vocanson M, Macari C, Poyet G, Herbelin A, Nicolas J, et al. Invariant NKT cells suppress CD8(+) T-cell-mediated allergic contact dermatitis independently of regulatory CD4(+) T cells. J Invest Dermatol. 2013;133:980-7 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TCR beta Monoclonal Antibody (H57-597), FITC

Catalog # :

MA5-17652

Quantity :

300 ug

Price :

US 371.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Armenian Hamster

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.2 ug/1x10^6 cells

Species :

Mouse

Clone :

H57-597

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles. Store in the dark.

Description :

The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease (ref5). T Cell and TCR Diversity Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP). A small number of T cells lack both CD4 and CD8 (double negative, DN). Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders. Gamma-delta T cells are primarily found within the epithelium. They show less TCR diversity and recognize antigens differently than alpha-beta T cells. Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.

Immunogen :

Affinity-purified DO-11.10 TCR

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.2 ug/1x10^6 cells

Aliases :

bTCR; FLJ22602; MGC117436; MGC22624; MGC23964; MGC71411; T cell receptor beta chain; t-cell antigen receptor; T-cell receptor; TCR beta; Tcra; Tcrb; TCRbeta; TCRD; Tib; TRA

more info or order :

Invitrogen product webpage