Cofilin Monoclonal Antibody (GT567) | Invitrogen MA5-17275 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cofilin Monoclonal Antibody (GT567)

catalog :

MA5-17275

quantity :

100 uL

price :

US 524.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GT567

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Ullo M, Logue J. ADF and cofilin-1 collaborate to promote cortical actin flow and the leader bleb-based migration of confined cells. elife. 2021;10: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Cofilin Monoclonal Antibody (GT567)

Catalog # :

MA5-17275

Quantity :

100 uL

Price :

US 524.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Species :

Human, Mouse, Rat

Clone :

GT567

Isotype :

IgG2a

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.

Immunogen :

Recombinant fragment contains a sequence corresponding to a region within amino acids 1 and 166 of Cofilin 1

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Aliases :

18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18