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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PEX19 Monoclonal Antibody (GT554)
catalog :
MA5-17266
quantity :
100 uL
price :
US 474.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GT554
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:400
  • western blot; human; 1:1000
Emmanouilidis L, Schütz U, Tripsianes K, Madl T, Radke J, Rucktäschel R, et al. Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19. Nat Commun. 2017;8:14635 pubmed publisher
Stork B, Dean A, Ortiz A, Saha P, Putluri N, Planas Silva M, et al. Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism. Mol Metab. 2022;62:101513 pubmed publisher
Liu L, Ma F, Hao Y, Yi Z, Yu X, Xu B, et al. Integrative Informatics Analysis of Transcriptome and Identification of Interacted Genes in the Glomeruli and Tubules in CKD. Front Med (Lausanne). 2020;7:615306 pubmed publisher
product information
Product Type :
Antibody
Product Name :
PEX19 Monoclonal Antibody (GT554)
Catalog # :
MA5-17266
Quantity :
100 uL
Price :
US 474.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: 1:50-1:200, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:10,000
Species :
Human, Mouse
Clone :
GT554
Isotype :
IgG2a
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS).
Immunogen :
Recombinant fragment contains a sequence corresponding to a region within amino acids 1 and 299 of PEX19
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:50-1:200, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:10,000
Aliases :
33 kDa housekeeping protein; D1S2223E; HK33; housekeeping gene, 33kD; OK/SW-cl.22; PBD12A; peroxin-19; Peroxisomal biogenesis factor 19; peroxisomal farnesylated protein; peroxisome biogenesis factor 19; Pex19; PMP1; PMPI; PxF; PXMP1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA