CK1 epsilon Monoclonal Antibody (AF6C1) | Invitrogen MA5-17231 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CK1 epsilon Monoclonal Antibody (AF6C1)

catalog :

MA5-17231

quantity :

100 µL

price :

US 454.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AF6C1

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

CK1 epsilon Monoclonal Antibody (AF6C1)

Catalog # :

MA5-17231

Quantity :

100 µL

Price :

US 454.00

Clonality :

Monoclonal

Purity :

Ammonium sulfate precipitation

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: Assay-dependent, Immunoprecipitation: 1 µL/400 µL lysate, Western Blot: 1:2,000

Species :

Human, Mouse, Rat

Clone :

AF6C1

Isotype :

IgG1

Storage :

-20°C

Description :

Casein kinases are a group of ubiquitous Ser/Thr kinases that phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a highly conserved kinase domain but differ in their variable N-and C-terminal domains. Mammals have seven family members: alpha, beta, gamma1, gamma2, gamma3, delta and epsilon. They all share at least 50% amino acid identity within the protein kinase catalytic domain. CK1 isoforms exclusively use ATP as phosphate donor and are generally co-factor independent. Casein kinase I epsilon is a Wnt-regulated kinase, and regulated phosphorylation of Dvl allows fine tuning of the Wnt-b-catenin signaling pathway. CKIe positively regulates Akt possibly by inhibiting PP2A. CKIe play an important role in neurodegenerative diseases.

Immunogen :

Recombinant human protein purified from E.coli (His-Casein Kinase Ie)

Format :

liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunoprecipitation: 1 µL/400 µL lysate, Western Blot: 1:2,000

Aliases :

AI426939; AI551861; AW457082; casein kinase 1; casein kinase 1 epsilon; casein kinase 1, epsilon; casein kinase I isoform epsilon; CK1e; CK1epsilon; CKI, epsilon; CKIe; CKIepsilon; CKI-epsilon; Csnk1e; HCKIE; KC1 epsilon; KC1epsilon; MGC10398; OTTHUMP00000063258; OTTHUMP00000063263; RP1-5O6.1; tau