This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
YAP1 Monoclonal Antibody (1A12)
catalog :
MA5-17200
quantity :
100 ug
price :
US 542.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1A12

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 1
Reference
Seo E, Jee B, Chung J, Song W, Sung H, Jeon H, et al. Repression of SLC22A3 by the AR-V7/YAP1/TAZ axis in enzalutamide-resistant castration-resistant prostate cancer. FEBS J. 2023;290:1645-1662 pubmed publisher
product information
Product Type :
Antibody
Product Name :
YAP1 Monoclonal Antibody (1A12)
Catalog # :
MA5-17200
Quantity :
100 ug
Price :
US 542.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human
Applications :
ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000
Species :
Human
Clone :
1A12
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.
Immunogen :
Purified recombinant fragment of human YAP1 expressed in E. Coli.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000
Aliases :
65 kDa Yes-associated protein; AI325207; cb194; CH211-181P1.5-001; COB1; Protein yorkie homolog; sb:cb194; si:ch211-181p1.5; si:dkey-3b8.3; transcriptional coactivator YAP1; wu:fc18c04; yap; Yap1; YAP2; Yap65; Yes associated protein 1; Yes1 associated transcriptional regulator; yes-associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; yes-associated protein, 65 kDa; Yki; Yorkie; yorkie homolog; zgc:158380; zYAP
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA