TWIST1 Monoclonal Antibody (2F8E7) | Invitrogen MA5-17195 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TWIST1 Monoclonal Antibody (2F8E7)

catalog :

MA5-17195

quantity :

100 ug

price :

US 542.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2F8E7

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

citations: 2

Reference
Wu H, Chen L, Chiu W, Tsai C. Kisspeptin Regulates Cell Invasion and Migration in Endometrial Cancer. J Endocr Soc. 2024;8:bvae001 pubmed publisher
Stampoultzis T, Guo Y, Nasrollahzadeh N, Rana V, Karami P, Pioletti D. Low-oxygen tension augments chondrocyte sensitivity to biomimetic thermomechanical cues in cartilage-engineered constructs. iScience. 2023;26:107491 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TWIST1 Monoclonal Antibody (2F8E7)

Catalog # :

MA5-17195

Quantity :

100 ug

Price :

US 542.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 1:10,000, Immunocytochemistry: 1:200, Western Blot: 1:500-1:2,000

Species :

Human

Clone :

2F8E7

Isotype :

IgG2b

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

TWIST1 acts as a transcriptional regulator. It inhibits myogensis by sequestering E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. TWIST1 also represses proinflammatory cytokines such as TNFA and IL1B. TWIST also regulates cranial suture patterning and fusion and gene expression differentially depending on dimer composition. Mutations in the gene are implicated in Saethre-Chotzen syndrome, a disease characterized by coronal synostosis, brachycephaly, low front hairline, facial asymmetry, hypertelorism, broad halluces, and clinodactyly.

Immunogen :

Purified recombinant fragment of human TWIST1 (amino acids: 9-74) expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Immunocytochemistry: 1:200, Western Blot: 1:500-1:2,000

Aliases :

AA960487; ACS3; B-HLH DNA binding protein; bHLHa38; BPES2; BPES3; charlie chaplin; class A basic helix-loop-helix protein 38; CRS; CRS1; CSO; H-twist; M-twist; p ACS3; Pde; pdt; Pluridigite; polydactyly EMS; SCS; Ska ; Ska m10Jus ; Ska10; Twist; twist basic helix-loop-helix transcription factor 1; twist family bHLH transcription factor 1; twist gene homolog 1; twist homolog 1; TWIST homolog of drosophila; Twist1; twist-related protein 1