Osteopontin Monoclonal Antibody (7C5H12) | Invitrogen MA5-17180 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Osteopontin Monoclonal Antibody (7C5H12)

catalog :

MA5-17180

quantity :

100 ug

price :

US 480.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7C5H12

reactivity :

human, domestic rabbit

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:200	Ding C, Qiao Z, Jiang W, Li H, Wei J, Zhou G, et al. Regeneration of a goat femoral head using a tissue-specific, biphasic scaffold fabricated with CAD/CAM technology. Biomaterials. 2013;34:6706-16 pubmed publisher
immunocytochemistry; domestic rabbit; 1:500	Guo J, Meng Z, Chen G, Xie D, Chen Y, Wang H, et al. Restoration of critical-size defects in the rabbit mandible using porous nanohydroxyapatite-polyamide scaffolds. Tissue Eng Part A. 2012;18:1239-52 pubmed publisher
	Chen W, Liu H, Huang X, Qian L, Chen L, Zhou Y, et al. A single-cell landscape of pre- and post-menopausal high-grade serous ovarian cancer ascites. iScience. 2023;26:107712 pubmed publisher
	Herrspiegel C, Plastino F, Lardner E, Seregard S, Williams P, Andr xe9 H, et al. A serum protein signature at the time of Uveal Melanoma diagnosis predicts long-term patient survival. BMC Cancer. 2023;23:277 pubmed publisher
	Krausgruber T, Redl A, Barreca D, Doberer K, Romanovskaia D, Dobnikar L, et al. Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation. Immunity. 2023;56:289-306.e7 pubmed publisher
	Žlajpah M, Bostjancic E, Tepes B, Zidar N. Expression of Extracellular Matrix-Related Genes and Their Regulatory microRNAs in Problematic Colorectal Polyps. Cancers (Basel). 2020;12: pubmed publisher
	Laçin N, İzol S, Ipek F, Tuncer M. Ganoderma lucidum, a promising agent possessing antioxidant and anti-inflammatory effects for treating calvarial defects with graft application in rats. Acta Cir Bras. 2019;34:e201900904 pubmed publisher
	Laçin N, Deveci E. Short-term use of resveratrol in alloplastic graft material applied with calvarial bone defects in rats. Acta Cir Bras. 2019;34:e201900704 pubmed publisher
	La xe7 in N, x130 zol B, G xf6 kalp xd6 zkorkmaz E, Deveci B, Deveci E. Effects of alloplastic graft material combined with a topical ozone application on calvarial bone defects in rats. Folia Morphol (Warsz). 2020;79:528-547 pubmed publisher
	Vidoni C, Ferraresi A, Secomandi E, Vallino L, Gardin C, Zavan B, et al. Autophagy drives osteogenic differentiation of human gingival mesenchymal stem cells. Cell Commun Signal. 2019;17:98 pubmed publisher
	Laçin N, İzol B, Ozkorkmaz E, Deveci B, Tuncer M. The effect of graft application and simvastatin treatment on tibial bone defect in rats. A histological and immunohistochemical study. Acta Cir Bras. 2019;34:e201900408 pubmed publisher
	Baloğlu M, Gokalp Ozkorkmaz E. Biochemical and immunohistochemical investigations on bone formation and remodelling in ovariectomized rats with tamoxifen citrate administration. Folia Morphol (Warsz). 2019;: pubmed publisher
	Laçin N, İzol B, Ozkorkmaz E, Deveci B, Tuncer M. The effect of graft application and allopurinol treatment on calvarial bone defect in rats1. Acta Cir Bras. 2019;34:e201900306 pubmed publisher
	Mazzoni E, D Agostino A, Manfrini M, Maniero S, Puozzo A, Bassi E, et al. Human adipose stem cells induced to osteogenic differentiation by an innovative collagen/hydroxylapatite hybrid scaffold. FASEB J. 2017;31:4555-4565 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Osteopontin Monoclonal Antibody (7C5H12)

Catalog # :

MA5-17180

Quantity :

100 ug

Price :

US 480.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000

Species :

Human

Clone :

7C5H12

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D.

Immunogen :

Purified recombinant fragment of human SPP1 (amino acids: 167-314) expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000

Aliases :

2AR; 2b7; 44 kDa bone phosphoprotein; Apl-1; BNSP; Bone sialoprotein 1; Bone sialoprotein 1 (BSPI/BSP1); Bsp; BSPI; Calcium oxalate crystal growth inhibitor protein; CALPHA1 fusion; Early T lymphocyte activation 1 (ETA1); early T-lymphocyte activation 1; early T-lymphocyte activation 1 protein; Eta; ETA-1; HGNC:11255; immunoglobulin alpha 1 heavy chain constant region fusion protein; MGC110940; Minopontin; nephropontin; Op; Opn; Opnl; OSP; osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; osteopontin-like protein; PSEC0156; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin bone sialoprotein I early T lymphocyte activation 1); secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); Secreted phosphoprotein 1 (SPP1); secreted phosphoprotein 1 variant 6; Sialoprotein (osteopontin); SPP1; SPP-1; SPP1/CALPHA1 fusion; unnamed protein product; urinar; urinary stone protein; Uropontin

more info or order :

Invitrogen product webpage