RUNX3 Monoclonal Antibody (2B3) | Invitrogen MA5-17169 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RUNX3 Monoclonal Antibody (2B3)

catalog :

MA5-17169

quantity :

100 ug

price :

US 546.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2B3

The same clone is also sold as:

Abcam: ab135248
Novus Biologicals: NBP2-37455
Bio-Rad: VMA00121

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Liang Y, Ding H. Expression levels of RUNX3 and FGFR2 in peripheral blood of severe acute pancreatitis and their clinical significance. Ann Surg Treat Res. 2023;104:90-100 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RUNX3 Monoclonal Antibody (2B3)

Catalog # :

MA5-17169

Quantity :

100 ug

Price :

US 546.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ChIP Assay: 2.5 ug/10^6 cells, ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000

Species :

Human, Mouse

Clone :

2B3

Isotype :

IgG2b

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Purified recombinant fragment of human RUNX3 (amino acids:186-252) expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 2.5 ug/10^6 cells, ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000

Aliases :

Acute myeloid leukemia 2 protein; acute myeloid leukemia gene 2; AML2; CBFA3; CBF-alpha 3; CBF-alpha-3; core binding factor alpha 3; core-binding factor subunit alpha-3; core-binding factor, runt domain, alpha subunit 3; oncogene AML-2; PEA2 alpha C; PEA2-alpha C; PEBP2 alpha C; PEBP2A3; PEBP2aC; PEBP2-alpha C; polyomavirus enhancer-binding protein 2 alpha C subunit; runt domain, alpha subunit 3; Runt related transcription factor 3; runt-related transcription factor 3; RUNX3; SL3/AKV core-binding factor alpha C subunit; SL3-3 enhancer factor 1 alpha C subunit; transcription factor AML2; transcription factor AML2/CBFA3