MEF2C Monoclonal Antibody (6H2G2) | Invitrogen MA5-17119 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MEF2C Monoclonal Antibody (6H2G2)

catalog :

MA5-17119

quantity :

100 ug

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6H2G2

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:500; loading ...; fig 3b	Duong E, Xiao J, Qi X, Nattel S. MicroRNA-135a regulates sodium-calcium exchanger gene expression and cardiac electrical activity. Heart Rhythm. 2017;14:739-748 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MEF2C Monoclonal Antibody (6H2G2)

Catalog # :

MA5-17119

Quantity :

100 ug

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000

Species :

Human, Mouse

Clone :

6H2G2

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. May also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.

Immunogen :

Purified recombinant fragment of human MEF2C (amino acids: 1-125) expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000

Aliases :

5430401D19Rik; 9930028G15Rik; AV011172; C5DELq14.3; DEL5q14.3; hoo; hoover; id:ibd5026; MADS box transcription enhancer factor 2, polypeptide C; Mef2; mef2c; mef2c protein; mef2ca; Myocyte enhancer factor 2C; myocyte enhancer factor 2C MEF2C; myocyte enhancer factor 2ca; myocyte enhancer factor 2ca 4'-6'; myocyte enhancer factor 2ca delta gamma-like; myocyte enhancer factor 2ca variant 4; myocyte enhancer factor 2ca variant 5; myocyte enhancer factor 2ca variant 6; myocyte enhancer factor 2ca; myocyte-specific enhancer factor 2C; myocyte-specific enhancer factor 2C; RGD1563119; wu:fc05b06; zgc:64184; zgc:85726

more info or order :

Invitrogen product webpage