KEAP1 Monoclonal Antibody (1F10B6) | Invitrogen MA5-17106 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KEAP1 Monoclonal Antibody (1F10B6)

catalog :

MA5-17106

quantity :

100 uL

price :

US 480.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1F10B6

The same clone is also sold as:

Novus Biologicals: NBP2-37433

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry, flow cytometry

citations: 3

Reference
Zeng H, Wang L, Zhang J, Pan T, Yu Y, Lu J, et al. Activated PKB/GSK-3β synergizes with PKC-δ signaling in attenuating myocardial ischemia/reperfusion injury via potentiation of NRF2 activity: Therapeutic efficacy of dihydrotanshinone-I. Acta Pharm Sin B. 2021;11:71-88 pubmed publisher
Jaén R, Fernandez Velasco M, Terrón V, Sánchez García S, Zaragoza C, Canales Bueno N, et al. BML-111 treatment prevents cardiac apoptosis and oxidative stress in a mouse model of autoimmune myocarditis. FASEB J. 2020;: pubmed publisher
Hsu J, Chang P, Cheng T, Kuo Y, Wu A, Tran T, et al. Identification of Withaferin A as a Potential Candidate for Anti-Cancer Therapy in Non-Small Cell Lung Cancer. Cancers (Basel). 2019;11: pubmed publisher

product information

Product Type :

Antibody

Product Name :

KEAP1 Monoclonal Antibody (1F10B6)

Catalog # :

MA5-17106

Quantity :

100 uL

Price :

US 480.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:50, Western Blot: 1:500-1:2,000

Species :

Human, Mouse

Clone :

1F10B6

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Immunogen :

Purified recombinant fragment of human KEAP1 (amino acids: 380-624) expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:50, Western Blot: 1:500-1:2,000

Aliases :

cytosolic inhibitor of Nrf2; INrf2; Keap1; kelch like ECH associated protein 1; Kelch-like ECH-associated protein 1; kelch-like family member 19; kelch-like protein 19; Kiaa0132; KLHL19; mKIAA0132; NRF2 cytosolic inhibitor; ring canal protein