HEXA Monoclonal Antibody (3F10) | Invitrogen MA5-17089 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HEXA Monoclonal Antibody (3F10)

catalog :

MA5-17089

quantity :

100 ug

price :

US 491.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3F10

reactivity :

Saccharomycetales, human, mouse

application :

western blot, ELISA, flow cytometry

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; Saccharomycetales	Watanabe Y, Kobayashi T, Yamamoto H, Hoshida H, Akada R, Inagaki F, et al. Structure-based analyses reveal distinct binding sites for Atg2 and phosphoinositides in Atg18. J Biol Chem. 2012;287:31681-90 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HEXA Monoclonal Antibody (3F10)

Catalog # :

MA5-17089

Quantity :

100 ug

Price :

US 491.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Western Blot: 1:500-1:2,000

Species :

Human, Mouse

Clone :

3F10

Isotype :

IgG2b

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

Immunogen :

Purified recombinant fragment of human HEXA expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Western Blot: 1:500-1:2,000

Aliases :

beta-hexosaminidase alpha-subunit; beta-hexosaminidase subunit alpha; Beta-hexosaminidase subunit beta; Beta-hexosaminidase subunit beta chain A; Beta-hexosaminidase subunit beta chain B; Beta-N-acetylhexosaminidase subunit alpha; beta-N-acetylhexosaminidase subunit beta; Cervical cancer proto-oncogene 7 protein; EC 3.2.1; EC 3.2.1.52; ENC-1AS; epididymis luminal protein 248; epididymis secretory protein Li 111; glycosidase; HCC7; HCC-7; HEL-248; HEL-S-111; Hex-1; HEXA; Hexb; hexosaminidase A; hexosaminidase A (alpha polypeptide); hexosaminidase A alpha; hexosaminidase B; hexosaminidase B (beta polypeptide); hexosaminidase subunit A; hexosaminidase subunit alpha; hexosaminidase subunit B; hexosaminidase subunit beta; Hexose aminidase A (alpha polypeptide); MGC99608; N-acetyl-beta-glucosaminidase subunit alpha; N-acetyl-beta-glucosaminidase subunit beta; TSD

more info or order :

Invitrogen product webpage