CK2 alpha-2 Monoclonal Antibody (1E1) | Invitrogen MA5-17062 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CK2 alpha-2 Monoclonal Antibody (1E1)

catalog :

MA5-17062

quantity :

100 uL

price :

US 480.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1.00E+01

reactivity :

human, mouse, rat

application :

western blot, ELISA, flow cytometry

citations: 2

Reference
Buelvas N, Ugarte Vio I, Asencio Leal L, Mu xf1 oz Uribe M, Martin Martin A, Rojas Fern xe1 ndez A, et al. Indomethacin Induces Spermidine/Spermine-N1-Acetyltransferase-1 via the Nucleolin-CDK1 Axis and Synergizes with the Polyamine Oxidase Inhibitor Methoctramine in Lung Cancer Cells. Biomolecules. 2023;13: pubmed publisher
Chen W, Lin Y, Lin L, Zhang B, Xu S, Wang W. Identification of potential candidate proteins for reprogramming spinal cord-derived astrocytes into neurons: a proteomic analysis. Neural Regen Res. 2021;16:2257-2263 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CK2 alpha-2 Monoclonal Antibody (1E1)

Catalog # :

MA5-17062

Quantity :

100 uL

Price :

US 480.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Rat

Clone :

1.00E+01

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Casein kinase II is a protein serine/threonine kinase that is thought to be present in all eukarotic cells, implying that it has fundamental cellular functions. The holoenzyme is a tetramer containing 2 alpha or alpha-prime subunits (or one of each) and 2 beta subunits. The function of beta subunits is unknown and the alpha subunit is the catalytic unit. CK2 functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alpha and alpha') in a homomeric or heteromeric conformation. Whilst the alpha- and alpha'-subunits are catalytically identical, proteins that regulate CK2, such as cdc2 and Hsp90, preferentially bind to the alpha and not the alpha'-subunit. CK2 can phosphorylate a number of key intracellular signaling proteins implicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-kappaB). CK2 is also thought to influence Wnt signaling via beta-catenin phosphorylation and the PI 3-K signaling pathway via the phosphorylation of Akt.

Immunogen :

Purified recombinant fragment of human CSNK2A2 (amino acids: 194-350) expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Western Blot: 1:500-1:2,000

Aliases :

1110035J23Rik; C77789; casein kinase 2 alpha; casein kinase 2 alpha'; casein kinase 2 alpha 2; casein kinase 2, alpha prime polypeptide; casein kinase II subunit alpha'; casein kinase II, alpha 2, polypeptide; CK II alpha'; CK2; CK2A2; CK2alpha'; CSNK2A1; CSNK2A2