This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
C17orf53 Monoclonal Antibody (7A3A9)
catalog :
MA5-17037
quantity :
100 ug
price :
US 491.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7A3A9

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, flow cytometry
product information
Product Type :
Antibody
Product Name :
C17orf53 Monoclonal Antibody (7A3A9)
Catalog # :
MA5-17037
Quantity :
100 ug
Price :
US 491.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human
Applications :
ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:50, Western Blot: 1:500-1:2,000
Species :
Human
Clone :
7A3A9
Isotype :
IgG2b
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
C17orf53 (chromosome 17 open reading frame 53) is a 647 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.
Immunogen :
Purified recombinant fragment of human C17ORF53 (amino acids: 282-527) expressed in E. Coli.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:50, Western Blot: 1:500-1:2,000
Aliases :
C17orf53; chromosome 17 open reading frame 53; uncharacterized protein C17orf53
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA