This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
BMPR1A Monoclonal Antibody (4B7B2)
catalog :
MA5-17036
quantity :
100 ug
price :
US 480.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4B7B2

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 2
Reference
Maruyama T, Stevens R, Boka A, DiRienzo L, Chang C, Yu H, et al. BMPR1A maintains skeletal stem cell properties in craniofacial development and craniosynostosis. Sci Transl Med. 2021;13: pubmed publisher
Browning L, Pietrzak M, Kuczma M, Simms C, Kurczewska A, Refugia J, et al. TGF-?-mediated enhancement of TH17 cell generation is inhibited by bone morphogenetic protein receptor 1? signaling. Sci Signal. 2018;11: pubmed publisher
product information
Product Type :
Antibody
Product Name :
BMPR1A Monoclonal Antibody (4B7B2)
Catalog # :
MA5-17036
Quantity :
100 ug
Price :
US 480.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human
Applications :
ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000
Species :
Human
Clone :
4B7B2
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
BMPR1A is a Type I member of the TGF beta receptor superfamily of transmembrane ser/thr kinases which phosphorylates intracellular SMADs in response to bone morphogenic proteins. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Immunogen :
Purified recombinant fragment of human BMPR1A (amino acids: 179-378 ) expressed in E. Coli.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000
Aliases :
10q23del; 1110037I22Rik; activin A receptor, type II-like kinase 3; activin receptor-like kinase 3; ACVRLK3; ALK3; ALK-3; AU045487; BMP type-1A receptor; BMP-2/BMP-4 receptor; Bmpr; Bmpr1a; BMPR-1A; BMPRIA; BMPR-IA; Bone morphogenetic protein 4 receptor; bone morphogenetic protein receptor type 1A; bone morphogenetic protein receptor type IA; bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor, type 1A; bone morphogenetic protein receptor, type IA; CD292; Serine/threonine-protein kinase receptor R5; SKR5
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA