CD31 Monoclonal Antibody (TLD-3A12) | Invitrogen MA5-16951 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD31 Monoclonal Antibody (TLD-3A12)

catalog :

MA5-16951

quantity :

500 ug

price :

US 748.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TLD-3A12

reactivity :

human, rat, rhesus macaque

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; rat	Ammar H, Saba S, Ammar R, Elsayed L, Ghaly W, Dhingra S. Erythropoietin protects against doxorubicin-induced heart failure. Am J Physiol Heart Circ Physiol. 2011;301:H2413-21 pubmed publisher
	Huang J, Yang R, Jiao J, Li Z, Wang P, Liu Y, et al. A click chemistry-mediated all-peptide cell printing hydrogel platform for diabetic wound healing. Nat Commun. 2023;14:7856 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD31 Monoclonal Antibody (TLD-3A12)

Catalog # :

MA5-16951

Quantity :

500 ug

Price :

US 748.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Rat, Rhesus Monkey

Applications :

ELISA: Assay-dependent, Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: 1:1,000

Species :

Human, Rat, Rhesus Monkey

Clone :

TLD-3A12

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

Immunogen :

Activated, Lewis rat derived microglial cells

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: 1:1,000

Aliases :

C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

more info or order :

Invitrogen product webpage