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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD34 Monoclonal Antibody (QBEND/10)
catalog :
MA5-16926
quantity :
200 ug
price :
US 524.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
QBEND/10
reactivity :
human, mouse, rat, bovine, domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 92
Published Application/Species/Sample/Dilution | Reference |
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| Tasli F, Vardar E, Argon A, Kabat T, Deniz S, Nart A, et al. Histochemical and immunohistochemical characteristics of elastofibromas. Pol J Pathol. 2014;65:120-4 pubmed
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| Yuan S, Guo Y, Zhou X, Shen W, Chen H. PDGFR-? (+) perivascular cells from infantile hemangioma display the features of mesenchymal stem cells and show stronger adipogenic potential in vitro and in vivo. Int J Clin Exp Pathol. 2014;7:2861-70 pubmed
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| Altinay S, Kusaslan R. Gastrointestinal autonomic nerve tumour of jejunum presenting as a perforated mass. J Pak Med Assoc. 2014;64:461-4 pubmed
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| Muică Nagy Bota M, Pap Z, Dénes L, Ghizdavăţ A, Brînzaniuc K, Lup Coşarcă A, et al. Immunohistochemical study of Ki67, CD34 and p53 expression in human tooth buds. Rom J Morphol Embryol. 2014;55:43-8 pubmed
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| Benedek Lázár E, Köpeczi J, Tunyogi A, Kakucs E, Horváth E, Turcu M, et al. Histopathological, immunophenotypic and clinical particularities and evolution of a case of hepatosplenic T-cell lymphoma in transformation to leukemia. Rom J Morphol Embryol. 2013;54:1135-9 pubmed
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| Chang I, Hsu C, Lin J, Hung C. The prognostic impact of MGMT expression on low-grade gangliogliomas: a clinicopathological and immunohistochemical study. Folia Neuropathol. 2013;51:275-82 pubmed
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| Bartoloni G, Pucci A, Giorlandino A, Berretta M, Mignosa C, Italia F, et al. Incidental Epstein-Barr virus associated atypical lymphoid proliferation arising in a left atrial myxoma: a case of long survival without any postsurgical treatment and review of the literature. Cardiovasc Pathol. 2013;22:e5-10 pubmed publisher
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| Kim H, Sung J, Park W, Kim Y. Gastrointestinal stromal tumors of the stomach with extensive calcification: report of two cases. Intern Med. 2012;51:2555-8 pubmed
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| Wallenfels I, Chlumska A. Vaginal myofibroblastoma with glands expressing mammary and prostatic antigens. Cesk Patol. 2012;48:40-3 pubmed
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| Gyftopoulos K, Vourda K, Sakellaropoulos G, Perimenis P, Athanasopoulos A, Papadaki E. The angiogenic switch for vascular endothelial growth factor-A and cyclooxygenase-2 in prostate carcinoma: correlation with microvessel density, androgen receptor content and Gleason grade. Urol Int. 2011;87:464-9 pubmed publisher
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| Petrilli G, Lorenzi L, Paracchini R, Ubiali A, Schumacher R, Cabassa P, et al. Epstein-Barr virus-associated adrenal smooth muscle tumors and disseminated diffuse large B-cell lymphoma in a child with common variable immunodeficiency: a case report and review of the literature. Int J Surg Pathol. 2014;22:712-21 pubmed publisher
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| Wang J, Huang W, Hu C, Guan X, Zhou H, Chen L. Relationship between RGS5 expression and differentiation and angiogenesis of gastric carcinoma. World J Gastroenterol. 2010;16:5642-6 pubmed
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| Gerritse R, Beerendonk C, Tijink M, Heetkamp A, Kremer J, Braat D, et al. Optimal perfusion of an intact ovary as a prerequisite for successful ovarian cryopreservation. Hum Reprod. 2008;23:329-35 pubmed
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| Ceyhan S, Onguru O, Baser I, Gunhan O. Expression of cyclooxygenase-2 and vascular endothelial growth factor in ovarian endometriotic cysts and their relationship with angiogenesis. Fertil Steril. 2008;90:988-93 pubmed
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| Zurita M, Vaquero J, Oya S, Bonilla C, Aguayo C. Neurotrophic Schwann-cell factors induce neural differentiation of bone marrow stromal cells. Neuroreport. 2007;18:1713-7 pubmed
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| Colla S, Tagliaferri S, Morandi F, Lunghi P, Donofrio G, Martorana D, et al. The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiog. Blood. 2007;110:4464-75 pubmed
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| Su Y, Vanderlaag K, Ireland C, Ortiz J, Grage H, Safe S, et al. 1,1-Bis(3'-indolyl)-1-(p-biphenyl)methane inhibits basal-like breast cancer growth in athymic nude mice. Breast Cancer Res. 2007;9:R56 pubmed
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| Lee F, Wen M, Wang J. Epithelioid angiosarcoma arising in a deep-seated plexiform schwannoma: a case report and literature review. Hum Pathol. 2007;38:1096-101 pubmed
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| Zheng P, Hop W, Luider T, Sillevis Smitt P, Kros J. Increased levels of circulating endothelial progenitor cells and circulating endothelial nitric oxide synthase in patients with gliomas. Ann Neurol. 2007;62:40-8 pubmed
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| Su Y, Ortiz J, Liu S, Bugge T, Singh R, Leppla S, et al. Systematic urokinase-activated anthrax toxin therapy produces regressions of subcutaneous human non-small cell lung tumor in athymic nude mice. Cancer Res. 2007;67:3329-36 pubmed
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| Behzatoglu K, Bahadir B. Malignant granular cell tumor with unusual histological features. Pathol Int. 2007;57:115-9 pubmed
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| El kott A, el Baz M, Mokhtar A. Proliferating cell nuclear antigen (PCNA) overexpression and microvessel density predict survival in the urinary bladder carcinoma. Int Urol Nephrol. 2006;38:237-42 pubmed
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| Lee J, Song Y, Ha H, Park J, Kim M, Park A, et al. Endothelial progenitor cells in pterygium pathogenesis. Eye (Lond). 2007;21:1186-93 pubmed
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| Namikoshi T, Satoh M, Horike H, Fujimoto S, Arakawa S, Sasaki T, et al. Implication of peritubular capillary loss and altered expression of vascular endothelial growth factor in IgA nephropathy. Nephron Physiol. 2006;102:p9-16 pubmed
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| El Kenawy A, Lotfy M, El Kott A, El Shahat M. Significance of matrix metalloproteinase 9 and CD34 expressions in esophageal carcinoma: correlation with DNA content. J Clin Gastroenterol. 2005;39:791-4 pubmed
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| Saglam E, Usubutun A, Kart C, Ayhan A, Kucukali T. Reactive nodular fibrous pseudotumor involving the pelvic and abdominal cavity: a case report and review of literature. Virchows Arch. 2005;447:879-82 pubmed
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| Uluoglu O, Akyurek N, Uner A, Coskun U, Ozdemir A, Gokcora N. Interdigitating dendritic cell tumor with breast and cervical lymph-node involvement: a case report and review of the literature. Virchows Arch. 2005;446:546-54 pubmed
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| Zheng P, van der Weiden M, Kros J. Differential expression of Hela-type caldesmon in tumour neovascularization: a new marker of angiogenic endothelial cells. J Pathol. 2005;205:408-14 pubmed
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| Damiani S, Eusebi V, Peterse J. Malignant neoplasms infiltrating pseudoangiomatous' stromal hyperplasia of the breast: an unrecognized pathway of tumour spread. Histopathology. 2002;41:208-15 pubmed
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| Greenberg A, Kerr W, Hammer D. Relationship between selectin-mediated rolling of hematopoietic stem and progenitor cells and progression in hematopoietic development. Blood. 2000;95:478-86 pubmed
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Ribaldone R, Piantanida P, Surico D, Boldorini R, Colombo N, Surico N. Aggressive angiomyxoma of the vulva. Gynecol Oncol. 2004;95:724-8 pubmed
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Lee J, Zhang X, Jung W, Chae Y, Park J, Kim I. DNA ploidy and c-Kit mutation in gastrointestinal stromal tumors. World J Gastroenterol. 2004;10:3475-9 pubmed
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Nielsen C, Williams J, van den Brink G, Lauwers G, Roberts D. Hh pathway expression in human gut tissues and in inflammatory gut diseases. Lab Invest. 2004;84:1631-42 pubmed
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Bildirici K, Donmez T, Gürlek E. Inflammatory pseudotumor of the kidney. Int Urol Nephrol. 2004;36:141-3 pubmed
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Joo H, Oh D, Kim Y, Lee K, Kim S. Increased expression of caveolin-1 and microvessel density correlates with metastasis and poor prognosis in clear cell renal cell carcinoma. BJU Int. 2004;93:291-6 pubmed
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Lee C, Lee M, Kang C, Kim Y, Park D, Kim J, et al. Differential expression of hypoxia inducible factor-1 alpha and tumor cell proliferation between squamous cell carcinomas and adenocarcinomas among operable non-small cell lung carcinomas. J Korean Med Sci. 2003;18:196-203 pubmed
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Molinero A, Penkowa M, Hernández J, Camats J, Giralt M, Lago N, et al. Metallothionein-I overexpression decreases brain pathology in transgenic mice with astrocyte-targeted expression of interleukin-6. J Neuropathol Exp Neurol. 2003;62:315-28 pubmed
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Levenberg S, Golub J, Amit M, Itskovitz Eldor J, Langer R. Endothelial cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A. 2002;99:4391-6 pubmed
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Khurana K, Mortelliti A. The role of fine-needle aspiration biopsy in the diagnosis and management of juvenile hemangioma of the parotid gland and cheek. Arch Pathol Lab Med. 2001;125:1340-3 pubmed
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product information
Product Type :
Antibody
Product Name :
CD34 Monoclonal Antibody (QBEND/10)
Catalog # :
MA5-16926
Quantity :
200 ug
Price :
US 524.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human, Non-human primate
Applications :
Flow Cytometry: 1:100-1:200, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:500-1:1,000, Immunomicroscopy: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Species :
Human, Non-human primate
Clone :
QBEND/10
Isotype :
IgG1
Storage :
4 C, do not freeze
Description :
CD34 is a highly glycosylated monomeric with a molecular weight range of 111-115 kDa surface protein that is present on many stem cell populations. CD34 is a stem cell marker although its expression on human hematopoietic stem cells is reversible. CD34 may serve as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions. CD34 is possibly an adhesion molecule with a putative role for mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Further, CD34 could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction. Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.
Immunogen :
Human endothelial cell membrane vesicles
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:100-1:200, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:500-1:1,000, Immunomicroscopy: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Aliases :
(E3-independent) E2 ubiquitin-conjugating enzyme R1; AU040960; CD34; CD34 antigen; CD34 molecule; CDC34; cell division cycle 34; cell division cycle 34 homolog; cluster designation 34; cluster of differentiation antigen 34; E2 ubiquitin-conjugating enzyme R1; E2-CDC34; hematopoietic progenitor cell antigen CD34; hematopoietic progenitor cell marker CD34; Mucosialin; RP11-328D5.2; sialomucin protein; type 1 transmembrane protein; UBC3; UBCH3; UBE2R1; ubiquitin carrier protein; ubiquitin conjugating enzyme E2 R1; ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1
more info or order :
company information

Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
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