This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
P-Selectin Monoclonal Antibody (Psel.KO.2.12)
catalog :
MA5-16922
quantity :
200 ug
price :
US 488.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Psel.KO.2.12

The same clone is also sold as:
reactivity :
domestic goat, human, rat, domestic sheep
application :
immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
product information
Product Type :
Antibody
Product Name :
P-Selectin Monoclonal Antibody (Psel.KO.2.12)
Catalog # :
MA5-16922
Quantity :
200 ug
Price :
US 488.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Goat, Human, Ovine, Rat
Applications :
Flow Cytometry: 1:50-1:100, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent
Species :
Goat, Human, Ovine, Rat
Clone :
Psel.KO.2.12
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. From there, it can be rapidly brought to the cell surface after exposure to thrombin, histamine, complement 5a, Ca21 ionophores, or adenosine diphosphate. P-selectin protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. P-selectin plays an important role in adhesive processes between leucocytes and endothelial cells, and is a calcium dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens found on neutrophils and monocytes. P-selectin is constitutively expressed in inflammation and contributes to atherogenesis, thrombosis and tissue destruction. Clinically, P-selectin is used to distinguish heparin induced thrombocytopenia with and without thrombosis.
Immunogen :
CD62P transfected 300.19 cells.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:50-1:100, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent
Aliases :
CD62; CD62 antigen-like family member P; CD62P; CD62P antigen; CD62P; CD62 homolog; FLJ45155; GMP140; GMP-140; GMRP; Granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; Grmp; LECAM3; leukocyte-endothelial cell adhesion molecule 3; PADGEM; Platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; PSEL; PSELECT; P-selectin; P-selectin precursor; RP1-86F14.2; selectin P; selectin P (granule membrane protein 140kDa, antigen CD62); selectin, platelet; Selp
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA