CD205 Monoclonal Antibody (NLDC-145) | Invitrogen MA5-16889 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD205 Monoclonal Antibody (NLDC-145)

catalog :

MA5-16889

quantity :

2 mL

price :

US 660.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

NLDC-145

reactivity :

mouse

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

citations: 10

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 4	Harimoto H, Shimizu M, Nakagawa Y, Nakatsuka K, Wakabayashi A, Sakamoto C, et al. Inactivation of tumor-specific CD8? CTLs by tumor-infiltrating tolerogenic dendritic cells. Immunol Cell Biol. 2013;91:545-55 pubmed publisher
flow cytometry; mouse	Lagranderie M, Nahori M, Balazuc A, Kiefer Biasizzo H, Lapa E Silva J, Milon G, et al. Dendritic cells recruited to the lung shortly after intranasal delivery of Mycobacterium bovis BCG drive the primary immune response towards a type 1 cytokine production. Immunology. 2003;108:352-64 pubmed
	Plantamura E, Dzutsev A, Chamaillard M, Djebali S, Moudombi L, Boucinha L, et al. MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype. Proc Natl Acad Sci U S A. 2018;115:10404-10409 pubmed publisher
	van Dinther D, Veninga H, Revet M, Hoogterp L, Olesek K, Grabowska J, et al. Comparison of Protein and Peptide Targeting for the Development of a CD169-Based Vaccination Strategy Against Melanoma. Front Immunol. 2018;9:1997 pubmed publisher
	Denzin L, Khan A, Virdis F, Wilks J, Kane M, Beilinson H, et al. Neutralizing Antibody Responses to Viral Infections Are Linked to the Non-classical MHC Class II Gene H2-Ob. Immunity. 2017;47:310-322.e7 pubmed publisher
	Lehmann C, Baranska A, Heidkamp G, Heger L, Neubert K, Lühr J, et al. DC subset-specific induction of T cell responses upon antigen uptake via Fc? receptors in vivo. J Exp Med. 2017;214:1509-1528 pubmed publisher
	Bogunovic M, Ginhoux F, Wagers A, Loubeau M, Isola L, Lubrano L, et al. Identification of a radio-resistant and cycling dermal dendritic cell population in mice and men. J Exp Med. 2006;203:2627-38 pubmed
	Bonifaz L, Bonnyay D, Charalambous A, Darguste D, Fujii S, Soares H, et al. In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination. J Exp Med. 2004;199:815-24 pubmed
	Takeda K, Yamaguchi N, Akiba H, Kojima Y, Hayakawa Y, Tanner J, et al. Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy. J Exp Med. 2004;199:437-48 pubmed
	Moron G, Rueda P, Casal I, Leclerc C. CD8alpha- CD11b+ dendritic cells present exogenous virus-like particles to CD8+ T cells and subsequently express CD8alpha and CD205 molecules. J Exp Med. 2002;195:1233-45 pubmed

product information

Product Type :

Antibody

Product Name :

CD205 Monoclonal Antibody (NLDC-145)

Catalog # :

MA5-16889

Quantity :

2 mL

Price :

US 660.00

Clonality :

Monoclonal

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:10 -1:25

Species :

Mouse

Clone :

NLDC-145

Isotype :

IgG2a

Storage :

4°C or -20°C if preferred

Description :

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.

Immunogen :

mouse lymphnode stroma emulsified in Freund's complete adjuvant

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:10 -1:25

Aliases :

CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4