CD2 Monoclonal Antibody (Mac288) | Invitrogen MA5-16807 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD2 Monoclonal Antibody (Mac288)

catalog :

MA5-16807

quantity :

2 mL

price :

US 349.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

Mac288

reactivity :

equine

application :

immunohistochemistry, flow cytometry, immunohistochemistry - frozen section

product information

Product Type :

Antibody

Product Name :

CD2 Monoclonal Antibody (Mac288)

Catalog # :

MA5-16807

Quantity :

2 mL

Price :

US 349.00

Clonality :

Monoclonal

Host :

Rat

Reactivity :

Equine

Applications :

Flow Cytometry: 1:200, Immunohistochemistry (Frozen): Assay Dependent

Species :

Equine

Clone :

Mac288

Isotype :

IgG2a

Storage :

4°C or -20°C if preferred

Description :

CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Morover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.

Immunogen :

Equine peripheral blood lymphocytes

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:200, Immunohistochemistry (Frozen): Assay Dependent

Aliases :

CD2 antigen, sheep red blood cell receptor, LFA-3 receptor, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, erythrocyte receptor, lymphocyte-function antigen-2, rosette receptor