This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TREM1 Monoclonal Antibody (L5-B8.2A12.3A12)
catalog :
MA5-16765
quantity :
500 ug
price :
US 644.00
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
L5-B8.2A12.3A12

The same clone is also sold as:
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
citations: 1
Reference
Yang F, Chiu P, Chen Y, Mak T, Chen N. TREM-1-dependent M1 macrophage polarization restores intestinal epithelium damaged by DSS-induced colitis by activating IL-22-producing innate lymphoid cells. J Biomed Sci. 2019;26:46 pubmed publisher
product information
Product Type :
Antibody
Product Name :
TREM1 Monoclonal Antibody (L5-B8.2A12.3A12)
Catalog # :
MA5-16765
Quantity :
500 ug
Price :
US 644.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 1:25-1:100, Functional Assay: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: Assay-dependent
Species :
Mouse
Clone :
L5-B8.2A12.3A12
Isotype :
IgG2a
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response. TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.
Immunogen :
Mouse TREM-1 Fc fusion protein
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:25-1:100, Functional Assay: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: Assay-dependent
Aliases :
CD354; sCD354; soluble CD354; soluble TREM 1; soluble TREM1; sTREM 1; sTREM1; TREM; Trem1; TREM-1; triggering receptor expressed in monocytes 1; triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA