Dectin 1 Monoclonal Antibody (GE2), FITC | Invitrogen MA5-16693 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Dectin 1 Monoclonal Antibody (GE2), FITC

catalog :

MA5-16693

quantity :

100 ug

price :

US 427.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

GE2

The same clone is also sold as:

Bio-Rad: MCA4661PE, MCA4661GA, MCA4661F, MCA4661FT, MCA4661EL, MCA4661A488
Abcam: Ab82888

reactivity :

human

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

Dectin 1 Monoclonal Antibody (GE2), FITC

Catalog # :

MA5-16693

Quantity :

100 ug

Price :

US 427.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Neat-1:10

Species :

Human

Clone :

GE2

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles. Store in the dark.

Description :

CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.

Immunogen :

NIH3T3 cells expressing full length Beta-glucan receptor.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Neat-1:10

Aliases :

Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082