CD68 Monoclonal Antibody (FA-11) | Invitrogen MA5-16674 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD68 Monoclonal Antibody (FA-11)

catalog :

MA5-16674

quantity :

250 ug

price :

US 666.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

FA-11

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:250; loading ...; fig 3f	Nies S, Takahashi H, Herber C, Huttner A, Chase A, Strittmatter S. Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β. J Biol Chem. 2021;297:101159 pubmed publisher
immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 2a	da Silva S, Marchi F, Su J, Yang L, Valverde L, Hier J, et al. Co-Overexpression of TWIST1-CSF1 Is a Common Event in Metastatic Oral Cancer and Drives Biologically Aggressive Phenotype. Cancers (Basel). 2021;13: pubmed publisher
immunohistochemistry; mouse; 1:300; loading ...; fig 4g	Song L, Chen X, Swanson T, LaViolette B, Pang J, Cunio T, et al. Lymphangiogenic therapy prevents cardiac dysfunction by ameliorating inflammation and hypertension. elife. 2020;9: pubmed publisher
flow cytometry; mouse; 1:200; loading ...; fig 4s1	Madel M, Ibáñez L, Ciucci T, Halper J, Rouleau M, Boutin A, et al. Dissecting the phenotypic and functional heterogeneity of mouse inflammatory osteoclasts by the expression of Cx3cr1. elife. 2020;9: pubmed publisher
flow cytometry; mouse; loading ...; fig s2d	Dunst J, Azzouz N, Liu X, Tsukita S, Seeberger P, Kamena F. Interaction between Plasmodium Glycosylphosphatidylinositol and the Host Protein Moesin Has No Implication in Malaria Pathology. Front Cell Infect Microbiol. 2017;7:183 pubmed publisher
	Li J, Fu G, Wang Y, Bian M, Xu Y, Zhang L, et al. The polarization of microglia and infiltrated macrophages in the injured mice spinal cords: a dynamic analysis. Peerj. 2023;11:e14929 pubmed publisher
	Xu Z, Zhang L, Huangfu N, Jiang F, Ji K, Wang S. Exploring the Effect and Mechanism of Si-Miao-Yong-An Decoction on Abdominal Aortic Aneurysm Based on Mice Experiment and Bioinformatics Analysis. Evid Based Complement Alternat Med. 2022;2022:4766987 pubmed publisher
	Douchi D, Yamamura A, Matsuo J, Lee J, Nuttonmanit N, Melissa Lim Y, et al. A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach. Cell Mol Gastroenterol Hepatol. 2022;13:1317-1345 pubmed publisher
	Toczek J, Boodagh P, Sanzida N, Ghim M, Salarian M, Gona K, et al. Computed tomography imaging of macrophage phagocytic activity in abdominal aortic aneurysm. Theranostics. 2021;11:5876-5888 pubmed publisher
	Mu H, Jiang Y, Xue L, Hua Y, Lin J, Cai Z. H3.3 K36M Mutation as a Clinical Diagnosis Method of Suspected Chondroblastoma Cases. Orthop Surg. 2021;13:616-622 pubmed publisher
	Chen J, Chen Y, Shi Y, Ding S, Shen L, Wang R, et al. VX-765 reduces neuroinflammation after spinal cord injury in mice. Neural Regen Res. 2021;16:1836-1847 pubmed publisher
	Chen Y, Wang S, Shi Y, Chen J, Ding S, Tang J, et al. CRID3, a blocker of apoptosis associated speck like protein containing a card, ameliorates murine spinal cord injury by improving local immune microenvironment. J Neuroinflammation. 2020;17:255 pubmed publisher
	Rogers R, Fournier M, Sanchez L, Ibrahim A, Aminzadeh M, Lewis M, et al. Disease-modifying bioactivity of intravenous cardiosphere-derived cells and exosomes in mdx mice. JCI Insight. 2019;4: pubmed publisher
	Roth Flach R, Su C, Bollinger E, Cortes C, Robertson A, Opsahl A, et al. Myeloperoxidase inhibition in mice alters atherosclerotic lesion composition. PLoS ONE. 2019;14:e0214150 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD68 Monoclonal Antibody (FA-11)

Catalog # :

MA5-16674

Quantity :

250 ug

Price :

US 666.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1:50-1:100, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Mouse

Clone :

FA-11

Isotype :

IgG2a

Storage :

4 C or -20 C if preferred

Description :

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Immunogen :

purified Con A acceptor glycoprotein from P815 cell line

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50-1:100, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen

more info or order :

Invitrogen product webpage