This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IL-10 Monoclonal Antibody (CC320)
catalog :
MA5-16619
quantity :
500 ug
price :
US 586.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CC320

The same clone is also sold as:
reactivity :
domestic goat, bovine, domestic sheep, domestic horse
application :
flow cytometry
product information
Product Type :
Antibody
Product Name :
IL-10 Monoclonal Antibody (CC320)
Catalog # :
MA5-16619
Quantity :
500 ug
Price :
US 586.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Bovine, Equine, Goat, Ovine
Applications :
ELISA: 5-10 ug/mL, Flow Cytometry: Assay-dependent, Functional Assay: Assay-dependent
Species :
Bovine, Equine, Goat, Ovine
Clone :
CC320
Isotype :
IgG1
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
Immunogen :
Plasmid cDNA encoding bovine IL-10
Format :
Liquid
Applications w/Dilutions :
ELISA: 5-10 ug/mL, Flow Cytometry: Assay-dependent, Functional Assay: Assay-dependent
Aliases :
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA