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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD38 Monoclonal Antibody (AT13/5)
catalog :
MA5-16578
quantity :
1 mg
price :
US 1112.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AT13/5
reactivity :
human
application :
immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human
Zuo Z, Tang Y, Bi C, Zhang W, Zhao S, Wang X, et al. Extraosseous (extramedullary) plasmacytomas: a clinicopathologic and immunophenotypic study of 32 Chinese cases. Diagn Pathol. 2011;6:123 pubmed publisher
Shipley M, Mangala Prasad V, Doepker L, Dingens A, Ralph D, Harkins E, et al. Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection. elife. 2021;10: pubmed publisher
Simonich C, Shipley M, Doepker L, Gobillot T, Garrett M, Cale E, et al. A diverse collection of B cells responded to HIV infection in infant BG505. Cell Rep Med. 2021;2:100314 pubmed publisher
Li T, Huang T, Du M, Chen X, Du F, Ren J, et al. Phosphorylation and chromatin tethering prevent cGAS activation during mitosis. Science. 2021;371: pubmed publisher
Doepker L, Danon S, Harkins E, Ralph D, Yaffe Z, Garrett M, et al. Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies. elife. 2021;10: pubmed publisher
Habekost M, Qvist P, Denham M, Holm I, Jørgensen A. Directly Reprogrammed Neurons Express MAPT and APP Splice Variants Pertinent to Ageing and Neurodegeneration. Mol Neurobiol. 2021;: pubmed publisher
Pariser D, Hilt Z, Ture S, Blick Nitko S, Looney M, Cleary S, et al. Lung megakaryocytes are immune modulatory cells. J Clin Invest. 2021;131: pubmed publisher
Ueda G, Antanasijevic A, Fallas J, Sheffler W, Copps J, Ellis D, et al. Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens. elife. 2020;9: pubmed publisher
Gu X, Wang Y, Li H, Li J, Wang S. Characteristics of Biohydrogen Production and Performance of Hydrogen-Producing Acetogen by Increasing Normal Molasses Wastewater Proportion in Anaerobic Baffled Reactor. Archaea. 2020;2020:8885662 pubmed publisher
Schumann B, MALAKER S, Wisnovsky S, Debets M, Agbay A, Fernandez D, et al. Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells. Mol Cell. 2020;78:824-834.e15 pubmed publisher
Chen C, Wang J, Zhao Y, Chen S, Hu Z, Chen L, et al. Enhancers Improve the AID-Induced Hypermutation in Episomal Vector for Antibody Affinity Maturation in Mammalian Cell Display. Antibodies (Basel). 2018;7: pubmed publisher
VerPlank J, Lokireddy S, Zhao J, Goldberg A. 26S Proteasomes are rapidly activated by diverse hormones and physiological states that raise cAMP and cause Rpn6 phosphorylation. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
Robinson D, Mammel A, Logan A, Larson A, Schmidt E, Condon A, et al. An In Vitro Model of Charcot-Marie-Tooth Disease Type 4B2 Provides Insight Into the Roles of MTMR13 and MTMR2 in Schwann Cell Myelination. ASN Neuro. 2018;10:1759091418803282 pubmed publisher
Gavin A, Huang D, Huber C, Martensson A, Tardif V, Skog P, et al. PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing. Nat Immunol. 2018;19:942-953 pubmed publisher
Bertagnon H, Batista C, Santos K, Gomes R, Bellinazzi J, Della Libera A. Alveolar macrophage functions during the transition phase to active immunity in calves. J Anim Sci. 2018;: pubmed publisher
Vondeling G, Menezes G, Dvortsin E, Jansman F, Konings I, Postma M, et al. Burden of early, advanced and metastatic breast cancer in The Netherlands. BMC Cancer. 2018;18:262 pubmed publisher
Calabrese D, Zlotkowski K, Alden S, Hewitt W, Connelly C, Wilson R, et al. Characterization of clinically used oral antiseptics as quadruplex-binding ligands. Nucleic Acids Res. 2018;46:2722-2732 pubmed publisher
Chen J, Sathiyamoorthy K, Zhang X, Schaller S, Perez White B, Jardetzky T, et al. Ephrin receptor A2 is a functional entry receptor for Epstein-Barr virus. Nat Microbiol. 2018;3:172-180 pubmed publisher
Dahal L, Dou L, Hussain K, Liu R, Earley A, Cox K, et al. STING Activation Reverses Lymphoma-Mediated Resistance to Antibody Immunotherapy. Cancer Res. 2017;77:3619-3631 pubmed publisher
Hoover C, Davenport K, Henderson D, Zabel M, Hoover E. Endogenous Brain Lipids Inhibit Prion Amyloid Formation In Vitro. J Virol. 2017;91: pubmed publisher
Hasegawa J, Sue M, Yamato M, Ichikawa J, Ishida S, Shibutani T, et al. Novel anti-EPHA2 antibody, DS-8895a for cancer treatment. Cancer Biol Ther. 2016;17:1158-1167 pubmed
Chutake Y, Lam C, Costello W, Anderson M, Bidichandani S. Reversal of epigenetic promoter silencing in Friedreich ataxia by a class I histone deacetylase inhibitor. Nucleic Acids Res. 2016;44:5095-104 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD38 Monoclonal Antibody (AT13/5)
Catalog # :
MA5-16578
Quantity :
1 mg
Price :
US 1112.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 1:100, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent
Species :
Human
Clone :
AT13/5
Isotype :
IgG1
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.
Immunogen :
Namalwa cells (hu B-cell line)
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:100, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent
Aliases :
2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; Cd38; CD38 antigen; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase); CD38 antigen (p45); CD38 antigen p45; CD38 molecule; CD38H; Cd38-rs1; cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; I-19; NAD(+) nucleosidase; NAD+ nucleosidase; NIM-R5 antigen; T10
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA