CD204 Monoclonal Antibody (2F8) | Invitrogen MA5-16494 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD204 Monoclonal Antibody (2F8)

catalog :

MA5-16494

quantity :

500 ug

price :

US 852.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

2F8

The same clone is also sold as:

OriGene: SM029LE, SM029B, SM029F, SM029FS, SM029P, AM26746PU-N, SM029R, SM029FT
Bio-Rad: MCA1322, MCA1322T, MCA1322PE, MCA1322FB, MCA1322FA, MCA1322A647, MCA1322A647T, MCA1322F, MCA1322A488, MCA1322GA, MCA1322EL, MCA1322BT, MCA1322A488T, MCA1322FT, MCA1322B, MCA1322A700
MyBioSource: MBS214942

reactivity :

mouse, pigs

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

citations: 1

Reference
Lin H, Faunce D, Stacey M, Terajewicz A, Nakamura T, Zhang Hoover J, et al. The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance. J Exp Med. 2005;201:1615-25 pubmed

product information

Product Type :

Antibody

Product Name :

CD204 Monoclonal Antibody (2F8)

Catalog # :

MA5-16494

Quantity :

500 ug

Price :

US 852.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Rat

Reactivity :

Fish, Mouse, Porcine

Applications :

ELISA: Assay-dependent, Flow Cytometry: 1:50-1:100, Functional Assay: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Fish, Mouse, Porcine

Clone :

2F8

Isotype :

IgG2b

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

CD204 gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. Diseases associated with MSR1 include Barrett Esophagus and Prostate Cancer.

Immunogen :

RAW264 cell line

Format :

Liquid

Applications w/Dilutions :

Aliases :

bovine scavenger receptor type II; CD204; Macrophage acetylated LDL receptor I and II; macrophage scavenger receptor 1; macrophage scavenger receptor type III; macrophage scavenger receptor types I and II; MRS-A; MSR; Msr1; MSR-A; phSR1; phSR2; RGD1564316; SCARA1; Scavenger receptor class A member 1; scavenger receptor class A, member 1; scavenger receptor type A; scavenger receptor type I; Scvr; SRA; SR-A; SR-AI; SR-AI/II; SR-AII