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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cytokeratin 8 Monoclonal Antibody (SP102)
catalog :
MA5-16420
quantity :
500 uL
price :
US 612.00
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
SP102
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 2
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:200; fig s2
  • immunocytochemistry; human; 1:200; fig 6
Lian X, Selekman J, Bao X, Hsiao C, Zhu K, Palecek S. A small molecule inhibitor of SRC family kinases promotes simple epithelial differentiation of human pluripotent stem cells. PLoS ONE. 2013;8:e60016 pubmed publisher
Parsons M, McCormick L, Janke L, Howard A, Bouchier Hayes L, Green D. Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice. Cell Death Differ. 2013;20:1174-82 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Cytokeratin 8 Monoclonal Antibody (SP102)
Catalog # :
MA5-16420
Quantity :
500 uL
Price :
US 612.00
Clonality :
Monoclonal
Purity :
Protein A/G
Host :
Rabbit
Reactivity :
Human
Applications :
Flow Cytometry: 1:200, Immunocytochemistry: 1:25-1:100, Immunohistochemistry (Frozen): 1:20, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:1,000
Species :
Human
Clone :
SP102
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Immunogen :
Synthetic peptide corresponding to C-terminus of human keratin 8.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:200, Immunocytochemistry: 1:25-1:100, Immunohistochemistry (Frozen): 1:20, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:1,000
Aliases :
AA960620; AL022697; AU019895; CARD2; cb186; CK8; CK-8; CYK8; CYKER; cytokeratin 8; cytokeratin 8 (370 AA); cytokeratin endo A; Cytokeratin-8; cytokeratin-A; DreK8; EndoA; etID33550.23; etID43142.23; etID43142.8; K2C8; K8; KERA; keratin 8; keratin 8, type II; keratin complex 2, basic, gene 8; keratin, type 2, gene 8; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8-like protein; keratin-8; KO; Krt-2.8; Krt2-8; krt8; LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8; sb:cb186; type II cytokeratin A (no.8); type-II keratin Kb8; wu:fa20h05; wu:fa95h10; wu:fb96c06; zfk8; zf-K8
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA