ICOS (CD278) Monoclonal Antibody (SP98) | Invitrogen MA5-16415 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ICOS (CD278) Monoclonal Antibody (SP98)

catalog :

MA5-16415

quantity :

500 uL

price :

US 622.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

SP98

reactivity :

human

application :

immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 1Be	Kim H, Ha S, Hong M, Heo S, Koh Y, Choi E, et al. PD-L1 expression on immune cells, but not on tumor cells, is a favorable prognostic factor for head and neck cancer patients. Sci Rep. 2016;6:36956 pubmed publisher
	Di Raimondo C, Rubio Gonzalez B, Palmer J, Weisenburger D, Zain J, Wu X, et al. Expression of immune checkpoint molecules programmed death protein 1, programmed death-ligand 1 and inducible T-cell co-stimulator in mycosis fungoides and Sézary syndrome: association with disease stage and clinical outcome. Br J Dermatol. 2022;187:234-243 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ICOS (CD278) Monoclonal Antibody (SP98)

Catalog # :

MA5-16415

Quantity :

500 uL

Price :

US 622.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:100

Species :

Human

Clone :

SP98

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

ICOS (CD278) encodes a protein that is a member of the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and has a crucial role in cell-cell signaling, immune responses, and the regulation of cell proliferation. ICOS has been linked to various disorders, including Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.

Immunogen :

Synthetic peptide corresponding to the C-terminus of human CD278

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:100

Aliases :

Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115

more info or order :

Invitrogen product webpage