SOX2 Monoclonal Antibody (SP76) | Invitrogen MA5-16399 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SOX2 Monoclonal Antibody (SP76)

catalog :

MA5-16399

quantity :

500 uL

price :

US 592.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

SP76

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:100; loading ...; fig s3b, s4 immunohistochemistry; human; 1:100; fig 6b	Koide T, Koyanagi Aoi M, Uehara K, Kakeji Y, Aoi T. CDX2-induced intestinal metaplasia in human gastric organoids derived from induced pluripotent stem cells. iScience. 2022;25:104314 pubmed publisher
	Kim D, Kim S, Sung A, Patel N, Wong N, Conboy M, et al. Autologous treatment for ALS with implication for broad neuroprotection. Transl Neurodegener. 2022;11:16 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SOX2 Monoclonal Antibody (SP76)

Catalog # :

MA5-16399

Quantity :

500 uL

Price :

US 592.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ChIP Assay: 5 uL/10^6 cells, Flow Cytometry: 1:200, Immunocytochemistry: 1:50-1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:100-1:500

Species :

Human, Mouse

Clone :

SP76

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.

Immunogen :

Synthetic peptide corresponding to N-terminus of human SOX-2 protein.

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 5 uL/10^6 cells, Flow Cytometry: 1:200, Immunocytochemistry: 1:50-1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:100-1:500

Aliases :

ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389

more info or order :

Invitrogen product webpage