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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
DOG-1 Recombinant Rabbit Monoclonal Antibody (SP31)
catalog :
MA5-16358
quantity :
500 uL
price :
US 676.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
SP31
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; fig s1
Dixit R, Kemp C, Kulich S, Seethala R, Chiosea S, Ling S, et al. TMEM16A/ANO1 is differentially expressed in HPV-negative versus HPV-positive head and neck squamous cell carcinoma through promoter methylation. Sci Rep. 2015;5:16657 pubmed publisher
  • immunohistochemistry; human; 1:50
Kakkar A, Mathur S, Jain D, Iyer V, Nalwa A, Sharma M. Utility of DOG1 Immunomarker in Fine Needle Aspirates of Gastrointestinal Stromal Tumor. Acta Cytol. 2015;59:61-7 pubmed publisher
  • immunohistochemistry; human; 1:80
Kemény L, Schnúr A, Czepán M, Rakonczay Z, Gál E, Lonovics J, et al. Na+/Ca2+ exchangers regulate the migration and proliferation of human gastric myofibroblasts. Am J Physiol Gastrointest Liver Physiol. 2013;305:G552-63 pubmed publisher
  • immunohistochemistry; human; 1:100; tbl 1
Lee P, Yau D, Lau P, Chan J. Plexiform fibromyxoma (plexiform angiomyxoid myofibroblastic tumor) of stomach: an unusual presentation as a fistulating abscess. Int J Surg Pathol. 2014;22:286-90 pubmed publisher
  • immunohistochemistry; human; 1:25
Kara T, Serinsoz E, Arpaci R, Gubur O, Orekici G, Ata A, et al. Contribution of DOG1 expression to the diagnosis of gastrointestinal stromal tumors. Pathol Res Pract. 2013;209:413-7 pubmed publisher
Vit O, Talacko P, Musil Z, Hartmann I, Pacak K, Petrak J. Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization. Clin Proteomics. 2023;20:39 pubmed publisher
Godse N, Khan N, Yochum Z, Gomez Casal R, Kemp C, Shiwarski D, et al. TMEM16A/ANO1 Inhibits Apoptosis Via Downregulation of Bim Expression. Clin Cancer Res. 2017;23:7324-7332 pubmed publisher
Güler B, Özyılmaz F, Tokuç B, Can N, Taştekin E. Histopathological Features of Gastrointestinal Stromal Tumors and the Contribution of DOG1 Expression to the Diagnosis. Balkan Med J. 2015;32:388-96 pubmed publisher
Hsieh M, Chou Y, Yeh S, Chang Y. Papillary-cystic pattern is characteristic in mammary analogue secretory carcinomas but is rarely observed in acinic cell carcinomas of the salivary gland. Virchows Arch. 2015;467:145-53 pubmed publisher
product information
Product Type :
Antibody
Product Name :
DOG-1 Recombinant Rabbit Monoclonal Antibody (SP31)
Catalog # :
MA5-16358
Quantity :
500 uL
Price :
US 676.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human
Applications :
Flow Cytometry: 1:20, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:1,000
Species :
Human
Clone :
SP31
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
DOG-1, the novel marker, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of kit or PDGFR alpha mutation status.
Immunogen :
Synthetic peptides of human DOG-1 protein (aa 400-500).
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:20, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:1,000
Aliases :
ANO1; anoctamin 1; anoctamin 1, calcium activated chloride channel; anoctamin-1; Ca2+-activated Cl- channel; calcium activated chloride channel; discovered on gastrointestinal stromal tumors protein 1; DOG1; FLJ10261; oral cancer overexpressed 2; Oral cancer overexpressed protein 2; ORAOV2; TAOS2; Tmem16a; Transmembrane protein 16A; transmembrane protein 16A (eight membrane-spanning domains); tumor-amplified and overexpressed sequence 2
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA