CD31 Monoclonal Antibody (SP38) | Invitrogen MA5-16337 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD31 Monoclonal Antibody (SP38)

catalog :

MA5-16337

quantity :

500 uL

price :

US 616.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

SP38

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:200; loading ...; fig 3c	Niethamer T, Stabler C, Leach J, Zepp J, Morley M, Babu A, et al. Defining the role of pulmonary endothelial cell heterogeneity in the response to acute lung injury. elife. 2020;9: pubmed publisher
immunohistochemistry; mouse	Fujimoto M, Tsuneyama K, Fujimoto T, Selmi C, Gershwin M, Shimada Y. Spirulina improves non-alcoholic steatohepatitis, visceral fat macrophage aggregation, and serum leptin in a mouse model of metabolic syndrome. Dig Liver Dis. 2012;44:767-74 pubmed publisher
immunohistochemistry; mouse	Miyama N, Dua M, Yeung J, Schultz G, Asagami T, Sho E, et al. Hyperglycemia limits experimental aortic aneurysm progression. J Vasc Surg. 2010;52:975-83 pubmed publisher
immunohistochemistry; mouse; 1:100	Yang H, Yang K, Hu J, Tang H, Zhang B, Chen Z, et al. Eukaryotic expression of extracellular ligand binding domains of murine Tie-2 and its anti-angiogenesis effect in SGC-7901 cell lines. J Gastroenterol Hepatol. 2010;25:345-51 pubmed publisher
immunohistochemistry; mouse	Huynh H, Ngo V, Koong H, Poon D, Choo S, Thng C, et al. Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma. J Cell Mol Med. 2009;13:2673-83 pubmed publisher
immunohistochemistry; rat	Seo Y, Yoon H, Park Y, Song K, Lee W, Park J. Correlation between scaffold in vivo biocompatibility and in vitro cell compatibility using mesenchymal and mononuclear cell cultures. Cell Biol Toxicol. 2009;25:513-22 pubmed publisher
immunohistochemistry; mouse	Huynh H, Ngo V, Fargnoli J, Ayers M, Soo K, Koong H, et al. Brivanib alaninate, a dual inhibitor of vascular endothelial growth factor receptor and fibroblast growth factor receptor tyrosine kinases, induces growth inhibition in mouse models of human hepatocellular carcinoma. Clin Cancer Res. 2008;14:6146-53 pubmed publisher
immunohistochemistry; mouse	Bell L, Cai L, Johnstone B, Traktuev D, March K, Considine R. A central role for hepatocyte growth factor in adipose tissue angiogenesis. Am J Physiol Endocrinol Metab. 2008;294:E336-44 pubmed
	McCormick A, Anderson T, Daugherity E, Okpalanwaka I, Smith S, Appiah D, et al. Targeting the pericyte antigen DLK1 with an alpha type-1 polarized dendritic cell vaccine results in tumor vascular modulation and protection against colon cancer progression. Front Immunol. 2023;14:1241949 pubmed publisher
	Abdel Latif R, Wadie W, Abdel Mottaleb Y, Abdallah D, El Maraghy N, El Abhar H. Reposition of the anti-inflammatory drug diacerein in an in-vivo colorectal cancer model. Saudi Pharm J. 2022;30:72-90 pubmed publisher
	Gonzalez H, Mei W, Robles I, Hagerling C, Allen B, Hauge Okholm T, et al. Cellular architecture of human brain metastases. Cell. 2022;185:729-745.e20 pubmed publisher
	Yao M, Ventura P, Jiang Y, Rodriguez F, Wang L, Perry J, et al. Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth. Cell. 2020;180:502-520.e19 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD31 Monoclonal Antibody (SP38)

Catalog # :

MA5-16337

Quantity :

500 uL

Price :

US 616.00

Clonality :

Monoclonal

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:50

Species :

Human

Clone :

SP38

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

Immunogen :

Synthetic peptide corresponding to C-terminus of mouse CD31

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50

Aliases :

C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

more info or order :

Invitrogen product webpage