CD23 Monoclonal Antibody (SP23) | Invitrogen MA5-16335 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD23 Monoclonal Antibody (SP23)

catalog :

MA5-16335

quantity :

500 µL

price :

US 626

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

SP23

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 4

Reference
Agaimy A, Michal M, Hadravsky L, Michal M. Follicular dendritic cell sarcoma: clinicopathologic study of 15 cases with emphasis on novel expression of MDM2, somatostatin receptor 2A, and PD-L1. Ann Diagn Pathol. 2016;23:21-8 pubmed publisher
Cubas R, Mudd J, Savoye A, Perreau M, van Grevenynghe J, Metcalf T, et al. Inadequate T follicular cell help impairs B cell immunity during HIV infection. Nat Med. 2013;19:494-9 pubmed publisher
Gualco G, Klumb C, Barber G, Weiss L, Bacchi C. Pediatric lymphomas in Brazil. Clinics (Sao Paulo). 2010;65:1267-77 pubmed
Gladkikh A, Potashnikova D, Korneva E, Khudoleeva O, Vorobjev I. Cyclin D1 expression in B-cell lymphomas. Exp Hematol. 2010;38:1047-57 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD23 Monoclonal Antibody (SP23)

Catalog # :

MA5-16335

Quantity :

500 µL

Price :

US 626

Clonality :

Monoclonal

Host :

Rabbit

Reactivity :

Human

Applications :

Flow Cytometry: 1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: Assay Dependent

Species :

Human

Clone :

SP23

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.

Immunogen :

Recombinant fragment within Human CD23 aa 1-250.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: Assay Dependent

Aliases :

BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; FCE2; Fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; Lymphocyte IgE receptor