TLR5 Monoclonal Antibody (19D759.2), FITC | Invitrogen MA5-16240 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TLR5 Monoclonal Antibody (19D759.2), FITC

catalog :

MA5-16240

quantity :

100µl

price :

US 349.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

19D759.2

reactivity :

human, mouse, dog

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

TLR5 Monoclonal Antibody (19D759.2), FITC

Catalog # :

MA5-16240

Quantity :

100µl

Price :

US 349.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Canine, Human, Mouse

Applications :

Flow Cytometry: 0.5-1 µg/10^6 cells

Species :

Canine, Human, Mouse

Clone :

19D759.2

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark

Description :

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Thirteen homologs of TLRs (TLR1-13) have been described. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens.

Immunogen :

Synthetic peptide (aa 708-724) of TLR5 protein.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5-1 µg/10^6 cells

Aliases :

RP11-239E10.1, SLEB1, TIL3, toll/interleukin-1 receptor-like protein 3