This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ROR gamma Monoclonal Antibody (4G419)
catalog :
MA5-16227
quantity :
100 ug
price :
US 474.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4G419

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, flow cytometry
citations: 1
Reference
Amir M, Chaudhari S, Wang R, Campbell S, Mosure S, Chopp L, et al. REV-ERBĪ± Regulates TH17 Cell Development and Autoimmunity. Cell Rep. 2018;25:3733-3749.e8 pubmed publisher
product information
Product Type :
Antibody
Product Name :
ROR gamma Monoclonal Antibody (4G419)
Catalog # :
MA5-16227
Quantity :
100 ug
Price :
US 474.00
Clonality :
Monoclonal
Purity :
Protein A/G
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
Flow Cytometry: 0.25-0.5 ug per million cells, Western Blot: 5 ug/mL
Species :
Human, Mouse, Rat
Clone :
4G419
Isotype :
IgG1, kappa
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
ROR gamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. Reports suggest thatROR gammais a ligand activated transcription factor and may be essential for lymphoid organogenesis (lymph nodes and Peyer's patches) and may play an important regulatory role in controlling apoptosis during thymopoiesis. ROR gamma inhibits the expression of Fas ligand and IL2 and directs the differentiation program of proinflammatory IL-17+ T helper cells. ROR gamma shares 50 to 51% sequence identity with RORA and RORB and is 88% identical to mouse ROR gamma. It is highly expressed in skeletal muscle and at lower levels in various other tissues.
Immunogen :
A portion of amino acids 1-50 of human ROR gamma
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25-0.5 ug per million cells, Western Blot: 5 ug/mL
Aliases :
IMD42; Nr1f3; Nuclear receptor ROR-gamma; nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; RAR related orphan receptor C; RAR-related orphan nuclear receptor variant 2; RAR-related orphan receptor C; RAR-related orphan receptor C, isoform a; RAR-related orphan receptor gamma; retinoic acid-binding receptor gamma; retinoid-related orphan receptor gamma; retinoid-related orphan receptor-gamma; RORC; RORG; RORgamma; RZRG; RZR-GAMMA; Thor; Thymus orphan receptor; TOR
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA