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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TLR8 Monoclonal Antibody (44C143), PE
catalog :
MA5-16194
quantity :
100 uL
price :
US 500.00
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
44C143
reactivity :
human, mouse
application :
immunohistochemistry, flow cytometry
more info or order :
Invitrogen product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 1c
van Haren S, Dowling D, Foppen W, Christensen D, Andersen P, Reed S, et al. Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization. J Immunol. 2016;197:4413-4424 pubmed
product information
Product Type :
Antibody
Product Name :
TLR8 Monoclonal Antibody (44C143), PE
Catalog # :
MA5-16194
Quantity :
100 uL
Price :
US 500.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse, Rabbit
Applications :
Flow Cytometry: 1 uL per million cells, Immunohistochemistry: Assay-Dependent
Species :
Human, Mouse, Rabbit
Clone :
44C143
Isotype :
IgG1, kappa
Storage :
4 C, store in dark
Description :
The TLR8 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The TLR8 gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Immunogen :
A KLH-conjugated synthetic peptide of human TLR8, within amino acids 750-850.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 uL per million cells, Immunohistochemistry: Assay-Dependent
Aliases :
CD antigen 288; CD288; TLR8; toll like receptor 8; toll-like receptor 8; UNQ249/PRO286
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA