TLR8 Monoclonal Antibody (44C143) | Invitrogen MA5-16190 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TLR8 Monoclonal Antibody (44C143)

catalog :

MA5-16190

quantity :

100 ug

price :

US 500.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

44C143

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, dot blot

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 1	Mitterreiter J, Ouwendijk W, van Velzen M, van Nierop G, Osterhaus A, Verjans G. Satellite glial cells in human trigeminal ganglia have a broad expression of functional Toll-like receptors. Eur J Immunol. 2017;47:1181-1187 pubmed publisher
flow cytometry; human; fig 1c	van Haren S, Dowling D, Foppen W, Christensen D, Andersen P, Reed S, et al. Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization. J Immunol. 2016;197:4413-4424 pubmed

product information

Product Type :

Antibody

Product Name :

TLR8 Monoclonal Antibody (44C143)

Catalog # :

MA5-16190

Quantity :

100 ug

Price :

US 500.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rabbit

Applications :

Dot Blot: Assay-Dependent, Flow Cytometry: 0.5-1 ug per million cells, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 1-3 ug/mL

Species :

Human, Mouse, Rabbit

Clone :

44C143

Isotype :

IgG1, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The TLR8 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The TLR8 gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

Immunogen :

KLH-conjugated synthetic peptide of human TLR8, within amino acids 750-850. It will cross-react with mouse TLR8.

Format :

Liquid

Applications w/Dilutions :

Dot Blot: Assay-Dependent, Flow Cytometry: 0.5-1 ug per million cells, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 1-3 ug/mL

Aliases :

CD antigen 288; CD288; TLR8; toll like receptor 8; toll-like receptor 8; UNQ249/PRO286

more info or order :

Invitrogen product webpage